Results 71 to 80 of about 3,827,941 (337)

Intervertebral disc transplantation: a biological approach to motion preservation [PDF]

open access: yesEuropean Spine Journal, 2008
Intervertebral disc transplantation was developed in a bipedal animal model through the stages of autograft, fresh allograft and fresh frozen allograft. Results showed that the allografts were able to survive through a deep freezing protocol and maintain cell viability after transplantation without significant immunoreaction.
Luk, KDK, Ruan, DK
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Exceptional preservation of soft tissue in a new specimen of Eoconfuciusornis and its biological implications

open access: yes, 2017
We report on an exceptional specimen of Eoconfuciusornis preserving rare soft-tissue traces of the ovary and wing. Ovarian follicles preserve a greater hierarchy than observed in Jeholornis and enantiornithines, suggesting confuciusornithiforms evolved ...
Xiaoting Zheng   +6 more
semanticscholar   +1 more source

Male fertility preservation and restoration strategies for patients undergoing gonadotoxic therapies

open access: yesBiology of Reproduction, 2022
Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility is an insidious disease that impacts not only the ability to have a biological child but also the emotional well-being of the infertile individuals ...
Kien T. Tran   +3 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Progress in Protein Interactomics Technologies and Their Applications to Plants Research

open access: yesGuangdong nongye kexue, 2022
Protein interactomics is a cutting-edge technology to identify and quantify the interaction of proteins with other metabolites or molecules like proteins, which has been an important part of plant systems biology and multi-omics research. In recent years,
Wenyang ZHANG   +3 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Maximal information component analysis: a novel non-linear network analysis method. [PDF]

open access: yes, 2013
BackgroundNetwork construction and analysis algorithms provide scientists with the ability to sift through high-throughput biological outputs, such as transcription microarrays, for small groups of genes (modules) that are relevant for further research ...
Bennett, Brian   +5 more
core   +3 more sources

Essential Oils: Chemical Composition and Diverse Biological Activities : A Comprehensive Review

open access: yesNatural Product Communications
Essential oils (EOs) are complex mixtures of volatile compounds, primarily terpenoids and phenolic constituents, derived from plants. They have been widely studied for their diverse biological activities, including antibacterial, antifungal, antiviral ...
Yamina Ben Miri
semanticscholar   +1 more source

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