Results 71 to 80 of about 3,722,975 (358)

Progress in Protein Interactomics Technologies and Their Applications to Plants Research

Guangdong nongye kexue, 2022
Protein interactomics is a cutting-edge technology to identify and quantify the interaction of proteins with other metabolites or molecules like proteins, which has been an important part of plant systems biology and multi-omics research. In recent years,
Wenyang ZHANG, Sheng ZHANG, Ganjun YI, Shijuan YAN   +3 more
doaj   +1 more source

Hygrothermal Performance of Worship Spaces: Preservation, Comfort and Energy Consumption [PDF]

, 2018
The energy problem, one the most important on a global scale, greatly affects the environment. Much of the current energy consumption occurs in existing buildings, including heritage buildings with varying protected status.
León-Rodríguez, Ángel Luís, Muñoz-Gonzalez, Carmen Maria, Suárez Medina, Rafael C., Teeling, Catherine   +3 more
core   +2 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Research Progress on the Regulation of Important Agronomic Traits in Crops by Non-coding Genetic Resources

Guangdong nongye kexue
In traditional crop genetics research, protein-coding genes have always been the primary focus. However, recent scientific advances have revealed the critical role of non-coding genetic resources in regulating key agronomic traits such as crop yield ...
Yang YU, Qingfeng ZHU, Jiao XUE, Pei CHEN, Yanzhao FENG   +4 more
doaj   +1 more source

An epistatic mini-circuitry between the transcription factors Snail and HNF4a controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs [PDF]

, 2012
Preservation of the epithelial state involves the stable repression of EMT program while maintenance of the stem compartment requires the inhibition of differentiation processes.
AMICONE, Laura, CICCHINI, Carla, Conigliaro A., Cozzolino A., Garibaldi F., Grassi G., MARCHETTI, ALESSANDRA, Santangelo L., TRIPODI, Marco   +8 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Answering open questions in biology using spatial genomics and structured methods [PDF]

arXiv, 2023
Genomics methods have uncovered patterns in a range of biological systems, but obscure important aspects of cell behavior: the shape, relative locations of, movement of, and interactions between cells in space. Spatial technologies that collect genomic or epigenomic data while preserving spatial information have begun to overcome these limitations ...
arxiv  

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Entanglement and coherence in pure and doped Posner molecules [PDF]

arXiv, 2023
The potential role of spin in biological systems is a primary topic in quantum biology. However, much of this research focuses on electron spin. A recent hypothesis suggests that nuclear spin may be better suited to biological processes, being less sensitive to decoherence.
arxiv