Results 71 to 80 of about 694,618 (154)

Targeting capacity, safety and efficacy of engineered extracellular vesicles delivered by transdermal microneedles to treat plasmacytoma in mice

Clinical and Translational Medicine, Volume 15, Issue 5, May 2025.
A schematic illustration of engineered EVs (CD38‐EVs‐Dox) delivered via MNs or intravenous administration for plasmacytoma treatment. CD38‐EVs encapsulated within MNs effectively enhanced tumour cell targeting compared to standard EVs in MNs and intravenously administered CD38‐EVs, with reduced lung and spleen distribution.
Yulin Cao, Xuan Hu, Di Wu, Yuxuan Jiang, Yali Yu, Shan Wang, Wenlan Chen, Yaoying Long, Liuyue Xu, Jiao Qu, Bianlei Yang, Blal Chakhabi, Hongxiang Wang, Yong Deng, Lei Chen, Zhichao Chen, Qiubai Li   +16 more
wiley   +1 more source

Tissue Engineering and Regenerative Medicine: Perspectives and Challenges

MedComm, Volume 6, Issue 5, May 2025.
Tissue engineering and regenerative medicine. This review presents cell therapy, extracellular vesicle therapy, and tissue engineering in regenerative medicine, highlighting their key historical milestones, clinical applications, and current challenges.
Van T. Hoang, Quyen Thi Nguyen, Trang Thi Kieu Phan, Trang H. Pham, Nhung Thi Hong Dinh, Le Phuong Hoang Anh, Lan Thi Mai Dao, Van Dat Bui, Hong‐Nhung Dao, Duc Son Le, Anh Thi Lan Ngo, Quang‐Duong Le, Liem Nguyen Thanh   +12 more
wiley   +1 more source

Advancing Medical Applications of Cancer Nanotechnology: Highlighting Two Decades of the NCI'S Nanotechnology Characterization Laboratory Service to the Research Community

WIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 3, May/June 2025.
The field of cancer nanomedicine has seen tremendous advancements over the last two decades, not only in the nanotechnologies themselves, but in the applications and uses of these novel nanomaterials and the characterization techniques employed to better understand both their physicochemical and biological properties. AI, artificial intelligence; QSAR,
Rachael M. Crist, Yechezkel Barenholz, Ahuva Cern, Kate N. Clark, Pieter R. Cullis, Cheryl Dean, Neil Desai, Mauro Ferrari, Matthieu Germain, Carmen A. Giacomantonio, Emma Grabarnik, Piotr Grodzinski, Atara Hod, Barry E. Kennedy, Ruvanthi N. Kularatne, Glen S. Kwon, Emmanuel Loeb, Erin B. Noftall, Len Pagliaro, Morteza Rasoulianboroujeni, Alexander Roth, Darren Rowles, Kulbir Singh, Nicole F. Steinmetz, Zhanna Yehtina, Yao Zhang, Daniel Zilbersheid, Jeffrey D. Clogston, Stephan T. Stern, Marina A. Dobrovolskaia   +29 more
wiley   +1 more source

Environmental safety during the administration of Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)

, 2016
Background: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative technique for intraperitoneal drug delivery. This study investigates the efficacy of the occupational health safety measures taken to prevent exposition of healthcare ...
Pedersen, Peter B, Graversen, Martin, Mortensen, Michael Bau; id_orcid   +2 more
core   +1 more source

Efficacy and safety of intraperitoneal chemotherapy for pancreatic cancer

BMC Surgery
Pancreatic cancer is a highly aggressive cancer with unfavorable prognosis despite the therapeutic interventions. Intraperitoneal chemotherapy has recently shown potential outcomes in the presence of peritoneal metastases.
Dorsa Safari, Mohammad Fakhrolmobasheri, Saeed Soleymanjahi   +2 more
doaj   +1 more source

New insights in the management of pseudomyxoma peritonei

Journal of Surgical Oncology, Volume 130, Issue 6, Page 1316-1325, November 2024.
Abstract While a rare entity, peritoneal pseudomyxoma treatment evolves. Decision‐making criteria improve with imaging development and exploratory laparoscopy. Surgery remains at the core of the therapeutic strategy whatever disease progression. Complete cytoreduction plus hyperthermic intraperitoneal chemotherapy (HIPEC) is standard of care. Iterative
Clément Pastier, I. H. J. T. De Hingh, Diane Goéré   +2 more
wiley   +1 more source

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) through a single port: alternative delivery for the control of peritoneal metastases.

, 2018
Peritoneal carcinomatosis is the natural course of gastrointestinal, gynecologic, and primary peritoneal neoplasms. In recent years, our understanding of carcinomatosis has changed; it is no longer considered a disseminated condition, but rather a ...
Rafael Seitenfus (5668709), Eduardo Dipp de-Barros (5668715), Guilherme Fedrizzi (5668718), Antonio Nocchi Kalil (5668712)   +3 more
core   +1 more source

Nanomedicine for cancer patient‐centered care

MedComm, Volume 5, Issue 11, November 2024.
Nanomedicine can satisfy the need for developing precision oncology, promote modern early diagnostic systems, monitoring the therapy based on the response of the individual patient, and provide precision antitumor immunotherapy and gene therapy, which can be developed with sophisticated experiments such as those made with organ‐on‐chip technology ...
Carlo Sorrentino, Stefania Livia Ciummo, Cristiano Fieni, Emma Di Carlo   +3 more
wiley   +1 more source

Occupational safety of pressurized intraperitoneal aerosol chemotherapy (PIPAC) [PDF]

, 2017
Background: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has emerged as a novel method to treat extensive, small volume peritoneal metastases.
Paul Sessink, Wim Ceelen, Sessink, Paul, Ceelen, Wim, Wouter Willaert, Willaert, Wouter   +5 more
core   +1 more source

Study on Performance of Nebulizer for Pressurized Intraperitoneal Aerosol Chemotherapy

Zhongguo yiliao qixie zazhi
ObjectiveThe study investigates the performance parameters of a nebulizer for pressurized intraperitoneal aerosol chemotherapy (PIPAC). MethodsLaser diffraction spectroscopy was used to measure the median droplet diameter (D50) and spray angle during the
Lanfeng ZHANG, Guangjun GUO, Guibing HOU
doaj   +1 more source