Results 261 to 270 of about 3,987,151 (271)

The Burden of Pretreatment HIV Drug Resistance in Trinidad and Tobago

AIDS Research and Human Retroviruses
Strategies to improve the scale-up of antiretroviral therapy (ART) for patients with HIV in Trinidad and Tobago, including the adoption of the “Test and Treat All” policy, have accompanied an increase in the number of patients with pretreatment HIV drug resistance (PDR) in the country.
Semiu O. Gbadamosi, Gregory Boyce, Mary Jo Trepka, Robert Jeffrey Edwards   +3 more
openaire   +2 more sources

Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia

European Journal of Haematology, 2001
Abstract: In 85 adult patients diagnosed with acute myeloid leukaemia (AML) and treated at the same institution during a 5‐yr period, the clinical significance of in vitro cellular drug resistance to the anthracyclines aclarubicin (Acla) and daunorubicin (Dau) as well as the nucleoside analogue cytarabine (Ara‐C) was investigated using a 4‐d MTT (3‐[4 ...
Nørgaard, Jan M., Langkjer, Sven Tyge, Palshof, Torben, Pedersen, B., Hokland, P.   +4 more
openaire   +3 more sources

HIV-1 pretreatment drug resistance negatively impacts outcomes of first-line antiretroviral treatment

AIDS, 2022
Introduction: Pretreatment drug resistance (PDR) prevalence in sub-Saharan Africa is rising, but evidence of its impact on efavirenz (EFV)-based antiretroviral treatment (ART) is inconclusive. We determined the impact of PDR on outcomes of EFV-based ART in a subanalysis of a randomized clinical trial comparing different ART ...
Lucas E, Hermans, Laura M, Hofstra, Rob, Schuurman, Rob, Ter Heine, David M, Burger, Stijn A J, Talboom, Dorien, De Jong, Hugo A, Tempelman, Willem D F, Venter, Monique, Nijhuis, Annemarie M J, Wensing   +10 more
openaire   +3 more sources

High-throughput sequencing reveals a high prevalence of pretreatment HIV-1 drug resistance in Sweden

AIDS, 2021
Objectives: HIV-1 pretreatment drug resistance (PDR) is a global concern. Our aim was to evaluate high-throughput sequencing (HTS) for HIV-1 resistance testing and describe PDR in Sweden, where 75% of diagnosed individuals are foreign-born. Design: Cross-sectional study.
Andersson, Emmi, Ambikan, Anoop, Brännström, Johanna, Aralaguppe, Shambhu G., Yilmaz, Aylin, Albert, Jan, Neogi, Ujjwal, Sönnerborg, Anders   +7 more
openaire   +2 more sources

HIV-1 Molecular Networks and Pretreatment Drug Resistance at the Frontier of Yunnan Province, China

AIDS Research and Human Retroviruses
The border areas of Yunnan Province in China are severely affected by human immunodeficiency virus (HIV). To investigate the risk of HIV transmission and assess the prevalence of pretreatment drug resistance (PDR) in the border area, blood samples were collected from individuals with newly reported HIV in 2021 in three border counties (Cangyuan, Gengma,
Yawen Wang, Cuiyun Yang, Xiaomei Jin, Huichao Chen, Qiongmei Zhu, Jie Dai, Lijuan Dong, Min Yang, Pengyan Sun, Rui Cao, Manhong Jia, Yanling Ma, Min Chen   +12 more
openaire   +2 more sources

Incidence of antimalarial pretreatment and drug sensitivity in vitro in multidrug-resistant Plasmodium falciparum infection in Thailand

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1998
Blood samples for determination of baseline antimalarial levels and sensitivity testing in vitro were collected from 411 patients with uncomplicated multidrug-resistant Plasmodium falciparum malaria (365 males, 46 females) before starting antimalarial treatment (62 in hospital and 349 as out-patients).
K, Congpuong, J, Sirtichaisinthop, P, Tippawangkosol, K, Suprakrob, K, Na-Bangchang, P, Tan-ariya, J, Karbwang   +6 more
openaire   +2 more sources

Clinical Impact of Pretreatment Human Immunodeficiency Virus Drug Resistance in People Initiating Nonnucleoside Reverse Transcriptase Inhibitor-Containing Antiretroviral Therapy: A Systematic Review and Meta-analysis.

Journal of Infectious Diseases, 2021
Silvia Bertagnolio, Seth C Inzaule, Collins C Iwuji   +2 more
exaly  

Prevalence of drug resistance mutations in Spain among both naive and pretreated patients.

Antiviral therapy, 2005
The ERASE Spanish Study Group was founded in 1997 with the primary objective of monitoring both the prevalence and impact of the development of resistance to antiretroviral drugs in HIV-infected sentinel populations. Two major studies, one in 1997 and another in 1998, have been conducted so far.
openaire   +1 more source

Pretreatment HIV Drug Resistance Among Adults Initiating or Re-Initiating First-Line Antiretroviral Therapy in Zimbabwe: Fast-Tracking the Transition to Dolutegravir-Based First-Line Regimens?

AIDS Research and Human Retroviruses, 2021
Chiratidzo Ellen Ndhlovu, David Katzenstein, Justen Manasa   +2 more
exaly  

Pretreatment drug resistance among people living with HIV from 2018 to 2022 in Guangzhou, China

Journal of Medical Virology
Linghua Li, Yun Lan, Liya Li
exaly