We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Jointly Production and Correlated Maintenance Optimization for Parallel Leased Machines
This paper deals with a preventive maintenance strategy optimization correlated to production for a manufacturing system made by several parallel machines under lease contract. In order to minimize the total cost of production and maintenance by reducing
Tarek ASKRI, Zied HAJEJ, Nidhal REZG
doaj +1 more source
Maintenance and Production Scheduling on a Single Machine with Stochastic Failures [PDF]
In this paper we study the problem of determining a production schedule for an order of n jobs on a single machine which is subject to stochastic machine failures.
Kiesmüller, Gudrun P. +1 more
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Optimization model for production scheduling taking into account preventive maintenance in an uncertainty-based production system. [PDF]
Penchev P, Vitliemov P, Georgiev I.
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The technical systems preventive maintenance trade-off model
A complex technical system preventive maintenance model based on a 'trade-off' between maximum availability and cost-effectiveness criterions was developed.
Svetomir Minić +2 more
doaj +1 more source
Smart Preventive Maintenance of Hybrid Networks and IoT Systems Using Software Sensing and Future State Prediction. [PDF]
Minea M, Minea VL, Semenescu A.
europepmc +1 more source
Breeding Particle Swarm Optimization for Railways Rolling Stock Preventive Maintenance Scheduling
Tarek Aboueldah, Hanan Farag
openalex +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

