Results 141 to 150 of about 49,072 (180)

Preclinical serum alterations and tissue changes in protein and gene expression of early cerebrospinal fluid-validated biomarkers in scrapie. [PDF]

Vet Res
Pérez-Lázaro S, Barrio T, Sevilla E, Bolea R, Badiola JJ.   +4 more
europepmc   +1 more source

Damping amyloid‐associated conformational fluctuations in a protein by an engineered diselenide bridge

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Polypeptide cross‐β assembly, characteristic of diverse proteotoxic diseases, defines a general thermodynamic ground state and limits the shelf lives of peptide‐ and protein therapeutics. A model is provided by insulin. Although the hormone contains a predominance of α‐helix, its fibrils exhibit cross‐β reorganization.
Yanwu Yang, Balamurugan Dhayalan, Andreas Ehnbom, Orit Weil‐Ktorza, Norman Metanis, Michael A. Weiss   +5 more
wiley   +1 more source

Involvement of the spleen in the anti-prion activity of hydroxypropyl methylcellulose in mice. [PDF]

Sci Rep
Teruya K, Oguma A, Nishizawa K, Doh-Ura K.   +3 more
europepmc   +1 more source

Advances in the nanostructure characterization of biological hydrogels formed by the prion‐like domain of EARLY FLOWERING 3

Acta Crystallographica Section D, Volume 82, Issue 8, Page 940-946, August 2026.
In biological systems, hydrogels often arise through liquid–liquid phase separation, where biomolecular condensates can age into gel‐like states. SAXS is a key technique to probe the molecular organization of these samples. This study introduces an in‐vacuum Gel‐Cell for SAXS‐based structural analysis of a biologically derived hydrogel formed by the ...
Stephanie Hutin, Pedro L. O. Filho, Anton M. Popov, Petra Pernot, Chloe Zubieta, Mark D. Tully   +5 more
wiley   +1 more source

Prion Protein Codon Implicated in Resistance in Dogs Detected in Non-Domesticated Members of Mammalia. [PDF]

Animals (Basel)
Wright EA, Lacy VA, Brugette GG, Roberts SM, Brookover EK, Hardy DM, Bradley RD.   +6 more
europepmc   +1 more source

Assessing the Conservation Status, Drivers of Threat and Available Occurrence Records of Sub‐Saharan African Freshwater Molluscs: Gaps and Patterns

African Journal of Ecology, Volume 64, Issue 6, August 2026.
ABSTRACT Freshwater molluscs are key bioindicators of ecosystem health, yet their conservation status and data coverage in sub‐Saharan Africa remain poorly understood. Mollusca is the third most evaluated phylum on the IUCN Red List in Africa, with 1394 species assessed (656 freshwater), of which 39.6% are Least Concern and 12% Critically Endangered ...
Marcel Kruger, Dewidine van der Colff, Wynand Malherbe   +2 more
wiley   +1 more source

Bovine Spongiform Encephalopathy: An Integrated Review of Prion Mechanisms, Neuroanatomy, and Control. [PDF]

Vet Sci
Marzola GP, Abuna RPF, Ribeiro LA, Parra JPRLL, Garcia MHH, Maria Barbalho S, Miglino MA.   +6 more
europepmc   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Concurrent Hashimoto's Encephalopathy and Papillary Thyroid Carcinoma: A Case Report

Clinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.
ABSTRACT Background Hashimoto's encephalopathy (HE) is a rare steroid‐responsive autoimmune syndrome. Although HE is associated with anti‐thyroid antibodies, its concurrence with malignant thyroid tumors has rarely been described and its clinical implications remain poorly understood.
Ryo Hara, Toshiyuki Kakumoto, Anna Suzuki, Satoshi Yamashita, Takayoshi Niwa, Kanako Hayashi, Arisa Morizono, Ayaka Sato, Masahiko Tanabe, Noritaka Kudo, Masashi Hamada, Wataru Satake, Tatsushi Toda   +12 more
wiley   +1 more source

Overlap of nonbreeding wandering albatrosses with fisheries and implications for colony‐specific population trajectories at South Georgia

Conservation Biology, Volume 40, Issue 4, August 2026.
Abstract Bycatch in fisheries is one of the most serious threats to pelagic seabirds, causing major population declines. Mitigation measures can reduce bycatch substantially, but many fisheries fail to apply best practices, and seabird mortality remains high.
V. Warwick‐Evans, E. J. Pearmain, R. A. Phillips   +2 more
wiley   +1 more source