Results 151 to 160 of about 49,072 (180)

Copper Coordination to the Prion Fragment (95-126): Implications for Neurodegenerative Diseases. [PDF]

Int J Mol Sci
Bacchella C, Ferraresi A, Monzani E, Dell'Acqua S.   +3 more
europepmc   +1 more source

Microtubules in Spinal Cord Injury: From Cytoskeletal Dysregulation to Therapeutic Regeneration

Journal of Neurochemistry, Volume 170, Issue 8, August 2026.
Graphical illustration of the microtubule interactome following spinal cord injury as potential targets for therapy. ABSTRACT Spinal cord injury (SCI) triggers an immediate and sustained disruption of the composition and organization of the neuronal cytoskeleton.
Itzhak Fischer, Peter W. Baas
wiley   +1 more source

Palliative care symptoms of people living with rapidly progressive prion diseases: a systematic review. [PDF]

BMC Palliat Care
Williams RT, White N, Kearns J, McNiven K, Marasigan AR, Sampson EL, Evans CJ, Mead S, Kupeli N, EMBED‐Care Programme.   +9 more
europepmc   +1 more source

Recombinant Human Collagen in Clinical Medicine

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Background Collagen is the dominant structural protein of vertebrate connective tissues and a central biomaterial in skin, cornea, tendon, cartilage, bone, vessel, oral mucosa, and wound repair. Traditional collagen products have largely been extracted from bovine, porcine, fish, or other animal tissues.
Kyu‐Ho Yi, Jong Keun Song, Hongseok Kim   +2 more
wiley   +1 more source

Water‐Mediated Phosphoryl Wires Stabilize Pathological Tau Fibrils

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
Extended 1D phosphoryl “wires” stabilize in‐register amyloid tau fibrils, as demonstrated by multiple‐quantum spin‐counting NMR, TEM, and MD simulations, using fibrils of tau peptide jR2R3‐P301L (tau295–313) with phosphorylation at S305 or Y310. ABSTRACT Hyperphosphorylation of tau is a hallmark of tauopathies, with specific phosphorylation sites ...
Lokeswara Rao Potnuru, Austin DuBose, Fiona Mon, Mesopotamia S. Nowotarski, Michael Vigers, Boqin Zhang, Chung‐Ta Han, John E. Straub, Songi Han   +8 more
wiley   +2 more sources

Theory and simulations of delayed stochastic and deterministic models of prion diseases. [PDF]

J Math Biol
Boregowda G, Sharif O, Gutierrez Iii D, Simmons A, Pujo-Menjouet L, Oraby T, Lindstrom MR.   +6 more
europepmc   +1 more source

Structural Heterogeneity of TDP‐43 Fragments in Alzheimer's Disease and Primary Age‐Related Tauopathy by Artificial Intelligence (AI)–Based 3D Segmentation

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
Immunostaining of anti‐phosphorylated TDP‐43 (pTDP‐43), TDP‐43 C‐terminal fragment (TDP‐43 C) and TDP‐43 N‐terminal fragment (TDP‐N), combined with an AI‐based object recognition, reconstruction and automatic 3D morphometric analysis pipeline in limbic regions revealed that distinct TDP‐43 fragment aggregation patterns, underscoring region‐specific ...
Gokhan Uruk, Rodolfo G. Gatto, Nadia Hossain, Jennifer L. Whitwell, R. Ross Reichard, Keith A. Josephs   +5 more
wiley   +1 more source

mGem: Cut4/Apc1 and its prion form at the cross roads of cell cycle regulation, heterochromatin organization, RNAi, stress response, and evolution. [PDF]

mBio
Sharma S, Singh J.
europepmc   +1 more source

Transgenic A53T Mice Have Astrocytic α‐Synuclein Aggregates in Dopamine and Striatal Regions

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
To identify whether astrocytes accumulate α‐synuclein aggregates before or after neurons, astrocytes from the midbrain and striatum of M83 A53T transgenic mice were compared to wild‐type. The substantia nigra pars compacta had more astrocytes than the ventral tegmental area or striatum, and small α‐synuclein aggregates were observed even within wild ...
Cormac Peat, Asheeta Prasad, David I. Finkelstein, Caroline Sue, Jennifer A. Johnston, Clare L. Parish, Lachlan Thompson, Deniz Kirik, Glenda M. Halliday   +8 more
wiley   +1 more source

Emerging risks at the vampire bat-prion interface: implications for wildlife, livestock, and public health. [PDF]

J Mammal
Frank LE, Bartz JC, Larsen PA.
europepmc   +1 more source