Results 221 to 230 of about 185,622 (273)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Optimizing virtual power plant coordination through locational marginal flexibility under network constraints. [PDF]

Sci Rep
Xie L, Li G, Xu M, Dong X, Tan Z.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Microbiome characterization of two fresh pork cuts during production in a pork fabrication facility. [PDF]

Microbiol Spectr
Asmus AE, Gaire TN, Schweisthal KJ, Staben SM, Noyes NR.   +4 more
europepmc   +1 more source

Dietary Cassava Roots Modified by Heat-Moisture Treatment Improve Performance, Glucose Metabolism, and Carcass Yield in Fattening Goats. [PDF]

Vet Med Int
Incharoen T, Foiklang S, Inyawilert W, Rattanapradit P, Likittrakulwong W, Moonmanee T, Loor JJ, Laorodphan N.   +7 more
europepmc   +1 more source

Evaluation of <i>Listeria monocytogenes</i> Dissemination in a Beef Steak Tartare Production Chain. [PDF]

Foods
Stella S, Sgoifo Rossi CA, Pomilio F, Centorotola G, Torresi M, Chiaverini A, Addis MF, Bernardi C, Penati M, Locatelli C, Moroni P, Grossi S, Fusi V, Urgesi P, Tirloni E.   +14 more
europepmc   +1 more source

The Effectiveness of Postharvest Processing on Microbiological Safety of Game Meat-A Systematic Review. [PDF]

Compr Rev Food Sci Food Saf
Ayaz ND, Aydin A, Bilska-Zając E, Branciari R, Deksne G, Economou V, Futoma-Kołoch B, Głogowski R, Neves EG, Jansen F, Korpysa-Dzirba W, Lauková A, Lazou T, Pálsdóttir GR, Peruzy MF, Prakas P, Ranucci D, Roila R, Różycki M, Rubiola S, Sakaridis I, Vieira-Pinto M.   +21 more
europepmc   +1 more source