Results 121 to 130 of about 83,365 (272)

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

A multi‐trait evaluation of patterns and fitness consequences of breeding phenology plasticity with nocturnal warming and food restriction in a lizard

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Faced with climate warming, ectothermic species shift their breeding phenology, which is in part attributed to an acceleration of gestation or incubation in warmer environments.
Théo Bodineau, Pierre de Villemereuil, Baptiste Lemaire, Simon Agostini, Beatriz Decencière, Matéo Millet, Sandrine Meylan, Jean‐François Le Galliard   +7 more
wiley   +1 more source

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

Integrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu, Ruiping Xu, Baofa Yin, Ruiyong Wu, Youheng Wei, Dehua Wang, Wanhong Wei   +6 more
wiley   +1 more source

Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency.

Journal of Clinical Endocrinology and Metabolism, 2019
CONTEXT No consensus exists for optimization of mineralocorticoid therapy in patients with primary adrenal insufficiency. OBJECTIVE To explore the relationship between mineralocorticoid replacement dose, plasma renin concentration (PRC) and clinically ...
R. Pofi, R. Pofi, A. Prete, V. Thornton-Jones, J. Bryce, S. Ali, S. F. Ahmed, A. Balsamo, F. Baronio, Amalia Cannuccia, Ayla Güven, T. Guran, F. Darendeliler, C. Higham, W. Bonfig, L. D. Vries, L. D. Vries, Tania A. S. S. Bachega, Mirela C Miranda, B. Mendonca, V. Iotova, M. Korbonits, N. Krone, R. Krone, A. Lenzi, Wiebke Arlt, Wiebke Arlt, R. Ross, A. Isidori, J. Tomlinson   +29 more
semanticscholar   +1 more source

Increased Mortality Risk in Patients With Primary and Secondary Adrenal Insufficiency [PDF]

, 2021
Kanchana Ngaosuwan, Desmond G. Johnston, Ian F. Godsland, Jeremy Cox, Azeem Majeed, Jennifer K Quint, Nick Oliver, Stephen T. Robinson   +7 more
openalex   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

The Roles of EDA2R in Ageing and Disease

Aging Cell, EarlyView.
Elevated expression of the ectodysplasin A2 receptor (EDA2R) has been linked to ageing and disease. We appraise the roles of EDA2R in these processes, exploring mechanisms of action, biomarker potential and therapeutic relevance of EDA2R in multiple contexts. ABSTRACT Ageing is a complex biological process driven, in part, by inflammaging.
Gemma Farrington, Lauren Tonge, Tracy Branagan, Sud Sudirman, Chao Fang, Louis Luk, Serkan Kir, Marco Bolis, Ildus I. Ahmetov, Kehinde Ross   +9 more
wiley   +1 more source

Association of polymorphic markers in innate immunity receptor genes with the risk of primary adrenal insufficiency

Медицинская иммунология
Primary adrenal insufficiency is a disease resulting from bilateral destruction of the adrenal cortex. The most common etiological factors are autoimmune disorders and infectious diseases, which indicates the key role of the immune system in the ...
N. D. Rasskazova, E. A. Meremyanina, N. O. Kalyuzhnaya, N. D. Abramova, E. V. Budanova, I. N. Diakov   +5 more
doaj   +1 more source

Pediatric Adrenal Insufficiency: Challenges and Solutions

Therapeutics and Clinical Risk Management, 2022
Daniela Nisticò,1 Benedetta Bossini,1 Simone Benvenuto,1 Maria Chiara Pellegrin,1 Gianluca Tornese2 1University of Trieste, Trieste, Italy; 2Department of Pediatrics, Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste ...
Nisticò D, Bossini B, Benvenuto S, Pellegrin MC, Tornese G   +4 more
doaj