Results 131 to 140 of about 44,382 (319)

Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis

open access: yesInternational Journal of Endocrinology, 2013
Delay of diagnosis of primary adrenal insufficiency (PAI) leads to adrenal crisis which is potentially lethal complication. The objective of our work was an assessment whether the establishment of diagnosis of adrenocortical insufficiency in Poland is ...
Lucyna Papierska, Michał Rabijewski
doaj   +1 more source

Deletion of NFIA Leads to Activation of S100A7 and Inflammatory Response‐Induced Apoptosis of Keratinocytes in Oral Lichen Planus Progression

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT S100 calcium‐binding protein A7 (S100A7) has been implicated in psoriasis and other inflammatory diseases. However, the function of S100A7 in oral lichen planus (OLP), a chronic inflammatory disease, remains unclear. OLP was induced in mice by transplanting human OLP lesions into the backs of thymus‐free mice, and an in vitro cell model was ...
Maimaiti Tudi   +3 more
wiley   +1 more source

Reduction of Rescue Treatment With Dupilumab for Chronic Rhinosinusitis With Nasal Polyps in Japan

open access: yesThe Laryngoscope, EarlyView.
This observational study examined the impact of add‐on dupilumab treatment on the use of rescue therapy in Japanese individuals with chronic rhinosinusitis with nasal polyps (CRSwNPs) using data from a large hospital‐based administrative claims database.
Mamoru Yoshikawa   +5 more
wiley   +1 more source

Adrenal Crisis Triggered by Endogenous Thyrotoxicosis: Case Series

open access: yesAACE Clinical Case Reports, 2018
: Objective: Describe a group of patients who presented with thyrotoxicosis and were also found to have adrenal insufficiency. Methods: Patient cases were collected over the past year at University of North Carolina at Chapel Hill.
Mazen Al Mushref, MD   +2 more
doaj  

Current Application Status and Innovative Development of Surgical Robot

open access: yesMed Research, EarlyView.
Advantage, Challenge and Innovation of surgical robots. ABSTRACT Surgery has undergone a revolutionary development since the innovations in anesthesiology, aseptic techniques, and antibiotics. The use of modern techniques, especially minimally invasive techniques, has led to a new era of microsurgery and reduced patient trauma.
Aimin Jiang   +11 more
wiley   +1 more source

Case report of Primary Adrenal Insufficiency

open access: yesPerspectives in Medical Research
Abstract Addison's disease, also known as primary adrenal insufficiency (PAI), is a rare endocrine disorder characterized by a decrease in all three adrenal hormones. This case report describes a 32-year-old female who presented with generalized weakness, fatigue, weight loss, and hyperpigmentation.
E Sandeep Reddy   +2 more
openaire   +2 more sources

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

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