Results 221 to 230 of about 44,382 (319)

PRIMARY ADRENAL LYMPHOMA WITH PRIMARY ADRENAL INSUFFICIENCY

, 2023
Farhana Ismail, Sivagurunathan Sutharsan, Sarah How, Siti Nazifah Md Rozi, Norlaila Mustafa, Norasyikin Abdul Wahab   +5 more
openalex   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Genetics of Primary Adrenal Insufficiency Beyond CAH in Saudi Arabian Population. [PDF]

Mol Genet Genomic Med
Al-Hamed MH, Qari A, Alrayes L, Alotaibi M, Al Masseri Z, Alotaibi A, AlAshwal A, AlHassnan ZN, Alsagheir A.   +8 more
europepmc   +1 more source

Assessment and classification of sex cord‐stromal tumours of the testis: recommendations from the testicular sex cord‐stromal tumour (TESST) group, an Expert Panel of the Genitourinary Pathology Society (GUPS) and International Society of Urological Pathology (ISUP)

Histopathology, EarlyView.
FH immunohistochemistry is recommended in clinically malignant Leydig cell tumours and in primary Leydig cell tumours with aggressive histopathologic features. Aims Testicular sex cord‐stromal tumours (TSCSTs) are relatively rare, accounting for ~5% of all testicular neoplasms.
Andres M Acosta, Maurizio Colecchia, Eva Comperat, Kristine M Cornejo, Anthony J Gill, Sounak Gupta, John C Cheville, Muhammad T Idrees, Chia‐Sui Kao, Fiona Maclean, Andres Matoso, Maria Rosaria Raspollini, Kvetoslava Michalova, Miguel Reyes Mugica, Satish K Tickoo, Toyonori Tsuzuki, Thomas M Ulbright, Sean R Williamson, Stephanie Siegmund, Lynette M Sholl, Pilar Gonzalez‐Peramato, Daniel M Berney   +21 more
wiley   +1 more source

PRIMARY ADRENAL INSUFFICIENCY SECONDARY TO ADRENAL TUBERCULOSIS IN A KLINEFELTER SYNDROME PATIENT

, 2023
Noor Hafis Md Tob, Norhaliza Mohd Ali, Bojlul Bahar   +2 more
openalex   +1 more source

Insights Into Pediatric Non-congenital Adrenal Hyperplasia: A Review Based on 5 Different Rare Cases with Primary Adrenal Insufficiency. [PDF]

Turk Arch Pediatr
Cetin SK, Siklar Z, Ozsu E, Aycan Z, Berberoglu M.   +4 more
europepmc   +1 more source

Prognostic Biomarkers for Anti‐PD‐1 Monoclonal Antibodies in the First Line Treatment of Advanced Melanoma

International Journal of Dermatology, EarlyView.
ABSTRACT Background Approximately 50% of patients with advanced melanoma treated with first‐line anti‐PD‐1 immunotherapy achieve clinical benefit. However, to date, there are no validated biomarkers for objective response (ORR), progression‐free survival (PFS), or overall survival (OS) with this treatment.
Marek Pásek, Emanuel Marques, Vojtěch Tretera, Petr Arenberger, Monika Arenbergerová, Jiří Šilar, David Šulc   +6 more
wiley   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Impact of Estimated Glomerular Filtration Rate and Serum C‐Reactive Protein Level to Overall Survival After Second‐Line Targeted Therapy Following Immuno‐Oncology Combination Therapy for Advanced Renal Cell Carcinoma

International Journal of Urology, EarlyView.
ABSTRACT Objectives Immune checkpoint inhibitor (ICI)‐based combination therapies are first‐line treatments for locally advanced or metastatic renal cell carcinoma (mRCC). However, second‐line treatment efficacy remains uncertain due to limited large randomized trials. This study evaluated real‐world oncological outcomes after second‐line treatments in
Keita Nakane, Hiromitsu Watanabe, Taku Naiki, Kiyoshi Takahara, Teruo Inamoto, Takahiro Yasui, Ryoichi Shiroki, Hideaki Miyake, Takuya Koie   +8 more
wiley   +1 more source

Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? – a systematic review

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader, Amy S. Garrett, Steven R. Pliszka   +2 more
wiley   +1 more source