Results 11 to 20 of about 4,431,933 (293)

Primary biliary cholangitis presenting as acute ischemic stroke: A rare association [PDF]

Clinical Case Reports, 2020
Primary biliary cholangitis is associated with hyperlipidemia, but studies show that the condition does not increase cardiovascular risks. The case presents acute ischemic stroke with no underlying risk factors and subsequent new diagnosis of primary ...
Bumsoo Park, Sumaiya Islam, Raghavendra C. Vemulapalli, Maria E. Shreve   +3 more
doaj   +3 more sources

A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression [PDF]

Nature Communications, 2023
Primary biliary cholangitis is a rare, chronic immune-mediated liver disease triggered by environmental exposures in genetically susceptible individuals.
You Li, Zhiqiang Li, Ruiling Chen, Min Lian, Hanxiao Wang, Yiran Wei, Zhengrui You, Jun Zhang, Bo Li, Yikang Li, Bingyuan Huang, Yong Chen, Qiaoyan Liu, Zhuwan Lyu, Xueying Liang, Qi Miao, Xiao Xiao, Qixia Wang, Jingyuan Fang, YongYong Shi, Xiangdong Liu, Michael F. Seldin, M. Eric Gershwin, Ruqi Tang, Xiong Ma   +24 more
doaj   +2 more sources

Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis [PDF]

Pathologica, 2021
Summary Autoimmune cholestatic liver diseases are rare hepato-biliary disorders characterized by a progressive, inflammatory destruction of bile ducts.
S. Sarcognato, D. Sacchi, F. Grillo, N. Cazzagon, L. Fabris, M. Cadamuro, I. Cataldo, C. Covelli, A. Mangia, M. Guido   +9 more
semanticscholar   +2 more sources

Pharmacotherapy for primary biliary cholangitis: an assessment of medication candidacy and rates of treatment [PDF]

BMC Gastroenterology
Background Ursodeoxycholic acid is the preferred first-line therapy for primary biliary cholangitis. Alternative therapies, such as obeticholic acid, are recommended for patients who cannot tolerate ursodeoxycholic acid or who have an inadequate response
Nicholas MacDonald, Rebecca Loh, Jonathan M. Fenkel, David A. Sass, Dina Halegoua-DeMarzio   +4 more
doaj   +3 more sources

Primary biliary cholangitis: Diagnosis and treatment

Liver Research, 2018
Primary biliary cholangitis (PBC) is an autoimmune disease that causes progressive destruction of the intrahepatic bile ducts. Although the pathogenesis of PBC is not completely understood, it is characterized by cholestatic inflammation resulting in a ...
Michael Chew, Christopher L. Bowlus
doaj   +2 more sources

A hepatic enigma: Pediatric presentation of primary biliary cholangitis. [PDF]

JPGN Rep
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Kasturi S, Schenker R, Shillingford N, Yanni G.   +3 more
europepmc   +2 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Primary biliary cholangitis: Epidemiology, prognosis, and treatment

Hepatology Communications, 2023
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the presence of antimitochondrial antibodies.
Juan Trivella, Binu V. John, C. Levy
semanticscholar   +1 more source

The role of miRNAs in the development of cholangiopathies. Part 1

Zdorovʹe Rebenka, 2023
The role of miRNA in the development of cholangiopathies is given in the scientific review. This article discusses the role of miRNA in primary sclerosing cholangitis and primary biliary cho­langitis.
A.E. Abaturov, V.L. Babуch
doaj   +1 more source