Results 11 to 20 of about 48,035 (283)
Baricitinib and primary biliary cholangitis
Journal of Translational Autoimmunity, 2021 Background and aims: There is an unmet need for alternative treatments for patients with primary biliary cholangitis (PBC) who do not respond to treatment with ursodeoxycholic acid (UDCA).
Stuart C. Gordon +7 more
doaj +3 more sources
Primary biliary cholangitis [PDF]
The Lancet, 2020 Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women. It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic cholangitis, with typical seroreactivity for antimitochondrial antibodies.
Ana, Lleo +3 more
+8 more sources
Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis
Pathologica, 2021 Autoimmune cholestatic liver diseases are rare hepato-biliary disorders characterized by a progressive, inflammatory destruction of bile ducts. Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the main autoimmune cholestatic liver diseases. Both may evolve into secondary biliary cirrhosis and its complications. Therapeutic
Samantha Sarcognato +9 more
openaire +4 more sources
Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis [PDF]
Seminars in Liver Disease, 2017 AbstractEpigenomics, the study of modifications to genetic material that do not alter the underlying DNA sequence, is generating increasing interest as a means to help clarify disease pathogenesis and outcomes. Although genome-wide association studies have identified several potential candidate genes that may be implicated in primary biliary ...
Angela C, Cheung +3 more
openaire +2 more sources
Pathophysiology of primary biliary cholangitis [PDF]
Best Practice & Research Clinical Gastroenterology, 2018 Primary biliary cholangitis is a prototypical autoimmune disease characterized by an overwhelming female predominance, a distinct clinical phenotype, and disease specific anti-mitochondrial antibodies targeted against a well-defined auto-antigen.
Aliya F, Gulamhusein +1 more
openaire +2 more sources
Epidemiology of Autoimmune Liver Disease
The Korean Journal of Gastroenterology, 2023 Autoimmune liver disease is an important immune-mediated pathologic entity involving the liver and intrahepatic bile duct, including autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis.
Nae-Yun Heo
doaj +1 more source
Primary Biliary Cholangitis with Ankylosing Spondylitis
The Korean Journal of Gastroenterology, 2022 Primary biliary cholangitis is a chronic inflammatory autoimmune liver disease that is characterized by a positive antimitochondrial antibodies test and progressive destruction of the small intrahepatic bile duct.
Young Mi Hong, Ki Tae Yoon, Mong Cho
doaj +1 more source
NAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
Primary biliary cholangitis presenting as acute ischemic stroke: A rare association
Clinical Case Reports, 2020 Primary biliary cholangitis is associated with hyperlipidemia, but studies show that the condition does not increase cardiovascular risks. The case presents acute ischemic stroke with no underlying risk factors and subsequent new diagnosis of primary ...
Bumsoo Park +3 more
doaj +1 more source
Annals of Hepatology, 2020 Primary biliary cholangitis and primary sclerosing cholangitis are rare diseases affecting the bile ducts and the liver. The limited knowledge of their pathogenesis leads to limited therapeutic options.
Alessio Gerussi +5 more
doaj +1 more source