Peribiliary glands are key in regeneration of the human biliary epithelium after severe bile duct injury [PDF]
, 2019 Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of luminal biliary epithelium has been proposed to activate PBG, resulting in cell proliferation ...
Carpino, Guido +15 more
core +6 more sources
Current understanding of primary biliary cholangitis [PDF]
Clinical and Molecular Hepatology, 2021 Primary biliary cholangitis (PBC) causes chronic and persistent cholestasis in the liver, eventually resulting in cirrhosis and hepatic failure without appropriate treatment.
Atsushi Tanaka
doaj +1 more source
Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]
, 2018 The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O +9 more
core +2 more sources
Serum micrornas as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma [PDF]
, 2016 The diagnosis of primary sclerosing cholangitis (PSC) is difficult due to the lack of sensitive and specific biomarkers, as is the early diagnosis of cholangiocarcinoma (CC), a complication of PSC.
Alpini, Gianfranco +17 more
core +2 more sources
A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]
, 2019 Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George +15 more
core +2 more sources
Osteoporosis in primary biliary cholangitis
World Journal of Gastroenterology, 2018 Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease with multiple debilitating complications. Osteoporosis is a common complication of PBC resulting in frequent fractures and leading to significant morbidity in this population, yet evidence for effective therapy is lacking.
Danford, Christopher J +4 more
openaire +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Novel Insights of Primary Sclerosing Cholangitis and Primary Biliary Cholangitis
The Korean Journal of Gastroenterology, 2020 Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are immune-mediated chronic liver diseases. PSC is a rare disorder characterized by multi-focal bile duct strictures and progressive liver diseases that ultimately results in the ...
Dong-Won Ahn
doaj +1 more source
Risk Factors for Immediate and Delayed-Onset Fever After Percutaneous Transhepatic Biliary Drainage [PDF]
, 2015 Objectives To prospectively investigate the pre and intraprocedural risk factors for immediate (IF) and delayedonset (DOF) fever development after percutaneous transhepatic biliary drainage (PTBD).
Bezzi, Mario +10 more
core +1 more source
Updated management of malignant biliary tract tumors: an illustrative review [PDF]
, 2016 The management of malignant biliary tumors (MBTs) is complex and requires a multidisciplinary approach. Guidelines and methods of staging for biliary tumors have recently been released by main international societies, altering the clinical and radiologic
Cannavale, Alessandro +6 more
core +1 more source