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Current understanding of primary biliary cholangitis [PDF]
Clinical and Molecular Hepatology, 2021 Primary biliary cholangitis (PBC) causes chronic and persistent cholestasis in the liver, eventually resulting in cirrhosis and hepatic failure without appropriate treatment.
Atsushi Tanaka
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Hepatology, 2018 This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009.
K. Lindor +4 more
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Journal of Hepatology, 2021 Backgrounds & Aims Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response to licensed medications, motivating
H. Cordell +42 more
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Obeticholic acid for the treatment of primary biliary cholangitis in adult patients: clinical utility and patient selection [PDF]
, 2016 Christopher L Bowlus Division of Gastroenterology and Hepatology, University of California Davis, Davis, CA, USA Abstract: Primary biliary cholangitis (PBC), previously known as primary biliary “cirrhosis”, is a rare autoimmune liver disease ...
Bowlus CL, Bowlus, Christopher L
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Clinical Gastroenterology and Hepatology, 2022 BACKGROUND AND AIMS GLIMMER assessed dose-response, efficacy, and safety of linerixibat, an ileal bile acid transporter inhibitor in development for cholestatic pruritus associated with primary biliary cholangitis (PBC). METHODS GLIMMER was a Phase 2b,
C. Levy +12 more
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Role of autoantibodies in the clinical management of primary biliary cholangitis
World Journal of Gastroenterology, 2023 Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by immune-driven destruction of small intrahepatic bile ducts leading a proportion of patients to hepatic failure over the years.
E. Rigopoulou, Dimitrios-Petrou Bogdanos
semanticscholar +1 more source
Medical Management of Chronic Cholestatic Liver Diseases
Canadian Journal of Gastroenterology, 2000 The purpose of the present review is to discuss the diagnosis and management of cholestatic liver diseases. Differential diagnoses to consider are described, including causes of extrahepatic biliary obstruction such as gallstones, strictures ...
Andrea A Gossard, Keith D Lindor
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BMC Gastroenterology, 2002 Background An increased prevalence of coeliac disease in patients with primary biliary cirrhosis has been recently reported. However, in other studies the association has not been confirmed.
Dimoulios Philippos +8 more
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Novel Insights of Primary Sclerosing Cholangitis and Primary Biliary Cholangitis
The Korean Journal of Gastroenterology, 2020 Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are immune-mediated chronic liver diseases. PSC is a rare disorder characterized by multi-focal bile duct strictures and progressive liver diseases that ultimately results in the ...
Dong-Won Ahn
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Preventative care in cholestatic liver disease: Pearls for the specialist and subspecialist
Liver Research, 2019 Cholestatic liver diseases (CLDs) encompass a variety of disorders of abnormal bile formation and/or flow. CLDs often lead to progressive hepatic insult and injury and following the development of cirrhosis and associated complications.
Adnan Malik +4 more
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