Primary biliary cholangitis: pathogenic mechanisms
Current Opinion in Gastroenterology, 2021 Purpose of review Primary biliary cholangitis (PBC) is characterized by autoimmune damage of intrahepatic bile ducts associated with a loss of tolerance to mitochondrial antigens. PBC etiopathogenesis is intriguing because of different perplexing features, namely: a) although mitochondria are present in all cell types and ...
Prieto, J. (Jesús) +2 more
openaire +5 more sources
Medical Management of Chronic Cholestatic Liver Diseases
Canadian Journal of Gastroenterology, 2000 The purpose of the present review is to discuss the diagnosis and management of cholestatic liver diseases. Differential diagnoses to consider are described, including causes of extrahepatic biliary obstruction such as gallstones, strictures ...
Andrea A Gossard, Keith D Lindor
doaj +1 more source
BMC Gastroenterology, 2002 Background An increased prevalence of coeliac disease in patients with primary biliary cirrhosis has been recently reported. However, in other studies the association has not been confirmed.
Dimoulios Philippos +8 more
doaj +1 more source
Preventative care in cholestatic liver disease: Pearls for the specialist and subspecialist
Liver Research, 2019 Cholestatic liver diseases (CLDs) encompass a variety of disorders of abnormal bile formation and/or flow. CLDs often lead to progressive hepatic insult and injury and following the development of cirrhosis and associated complications.
Adnan Malik +4 more
doaj +1 more source
Sarcoidosis and primary biliary cholangitis in a patient with cholestasis
Терапевтический архив, 2021 Primary biliary cholangitis and sarcoidosis are both cholestatic liver diseases. Currently, there are no established specific criteria for distinguishing the diseases from each other; diagnosis is based on the anamnesis, as well as the results of ...
M. Yu. Brovko +8 more
doaj +1 more source
Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]
, 1988 A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini +25 more
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Difficulties in Diagnosing Isolated IgG4-associated Sclerosing Cholangitis
Journal of Digestive Endoscopy, 2019 The most common causes of recurrent cholangitis are biliary stones and neoplasia. Primary types of sclerosing cholangitis such as IgG4-associated sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are rare causes of recurrent ...
Gábor Zsóri +3 more
doaj +1 more source
Development of colon cancer after liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis [PDF]
, 1990 Between February 26, 1981, and July 30, 1987, 36 patients underwent orthotopic liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis.
Higashi, H +5 more
core +1 more source
Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
Angewandte Chemie, EarlyView.The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +2 more sources
Association of diverse bacterial communities in human bile samples with biliary tract disorders: a survey using culture and polymerase chain reaction-denaturing gradient gel electrophoresis methods [PDF]
, 2016 Bacterial infection is considered a predisposing factor for disorders of the biliary tract. This study aimed to determine the diversity of bacterial communities in bile samples and their involvement in the occurrence of biliary tract diseases. A total of
Alebouyeh, M. +5 more
core +1 more source