Results 61 to 70 of about 4,431,933 (293)

Risk of fractures and postfracture mortality in 3980 people with primary biliary cholangitis: A population‐based cohort study

Journal of Internal Medicine, 2023
Morbidity in primary biliary cholangitis (PBC) is multifactorial. Osteoporosis related to cholestasis is an extrahepatic complication of PBC. It is not fully established to what extent people with PBC have an increased risk for fractures, and if ...
J. Schönau, A. Wester, J. Schattenberg, Hannes Hagström   +3 more
semanticscholar   +1 more source

Sarcoidosis and primary biliary cholangitis in a patient with cholestasis

Терапевтический архив, 2021
Primary biliary cholangitis and sarcoidosis are both cholestatic liver diseases. Currently, there are no established specific criteria for distinguishing the diseases from each other; diagnosis is based on the anamnesis, as well as the results of ...
M. Yu. Brovko, L. A. Akulkina, M. V. Kalashnikov, T. P. Rozina, T. P. Nekrasova, V. I. Sholomova, D. V. Konovalov, A. Sh. Yanakayeva, S. V. Moiseev   +8 more
doaj   +1 more source

Targeting Gut Microbiota for the Treatment of Primary Biliary Cholangitis: From Bench to Bedside

Journal of Clinical and Translational Hepatology, 2023
Primary biliary cholangitis (PBC) is a complex cholestatic liver disease with an unresolved etiology. The gut microbiota is composed of a dynamic community of bacteria, archaea, fungi, and viruses that have a key role in physiological processes related ...
Li Zhang, Ling Yang, Hui-Kuan Chu
semanticscholar   +1 more source

Environmental basis of primary biliary cholangitis [PDF]

, 2018
Autoimmunity is a consequence of both genetic and environmental factors, occurring in genetically susceptible hosts with environmental triggers. While genome-wide association studies have revealed a number of susceptible genes contributing to etiology ...
M Eric Gershwin, Atsushi Tanaka, Patrick SC Leung, Gershwin, M, Leung, Patrick, Tanaka, Atsushi   +5 more
core   +1 more source

Difficulties in Diagnosing Isolated IgG4-associated Sclerosing Cholangitis

Journal of Digestive Endoscopy, 2019
The most common causes of recurrent cholangitis are biliary stones and neoplasia. Primary types of sclerosing cholangitis such as IgG4-associated sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are rare causes of recurrent ...
Gábor Zsóri, Dóra Illés, László Tiszlavicz, László Czakó   +3 more
doaj   +1 more source

The causal effects of inflammatory bowel disease on primary biliary cholangitis: A bidirectional two‐sample Mendelian randomization study

Liver international (Print), 2023
Observational studies have indicated that the incidence of primary biliary cholangitis (PBC) is higher in inflammatory bowel disease (IBD) patients than that in healthy people. However, whether the correlation is causal remains unclear.
Hongchen Zhang, Lan-Lan Chen, Zhongqi Fan, Guoyue Lv   +3 more
semanticscholar   +1 more source

EMERGING THERAPIES IN PRIMARY BILIARY CHOLANGITIS: OVERVIEW OF CLINICALTRIALS.GOV [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Background: Primary biliary cholangitis (PBC) is an autoimmune disorder leading to different hepatic disorders. Progressive bile duct damage could result in cirrhosis.
Nasser Alorfi, Mansour Alourfi, Saeed Alsharif, Mohannad Aljehani, Abdulmalik Alsabban, Mohammad Almatrafi, Ysear Zakri, Abdullah AlMahmoud, Monther Ghunaiem, Rami Almalki, Ibrahim Aljerary, Abdullah Alkhattabi   +11 more
doaj   +1 more source

APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis

Hepatology International, 2022
Hong You1 · Xiong Ma2 · Cumali Efe3 · Guiqiang Wang4 · Sook‐Hyang Jeong5 · Kazumichi Abe6 · Weijia Duan1 · Sha Chen1 · Yuanyuan Kong7 · Dong Zhang8 · Lai Wei9 · Fu‐Sheng Wang10 · Han‐Chieh Lin11 · Jin Mo Yang12 · Tawesak Tanwandee13 · Rino A.
H. You, Xiong Ma, C. Efe, Gui-Qiang Wang, S. Jeong, K. Abe, Wei-Jia Duan, Sha Chen, Yuan-Yuan Kong, Dong Zhang, Lai Wei, Fu-Sheng Wang, Han-Chieh Lin, Jin-Mo Yang, T. Tanwandee, R. Gani, D. Payawal, B. C. Sharma, Jin-Lin Hou, O. Yokosuka, A. Dokmeci, Darrell Crawford, J. Kao, T. Piratvisuth, D. Suh, L. Lesmana, J. Sollano, G. Lau, S. Sarin, M. Omata, Atsushi Tanaka, J. Jia   +31 more
semanticscholar   +1 more source

Gut microbiota-derived butyrate induces epigenetic and metabolic reprogramming in myeloid-derived suppressor cells to alleviate primary biliary cholangitis.

Gastroenterology
BACKGROUND & AIMS Gut dysbiosis and myeloid-derived suppressor cells (MDSCs) are implicated in primary biliary cholangitis (PBC) pathogenesis. However, it remains unknown whether gut microbiota or their metabolites can modulate MDSCs homeostasis to ...
Rui Wang, Bo Li, Bingyuan Huang, Yi-Kang Li, Qiaoyan Liu, Zhuwan Lyu, Rui-Ling Chen, Qiwei Qian, Xueying Liang, Xiting Pu, Yi Wu, Yu Chen, Q. Miao, Qi-Xia Wang, M. Lian, Xiao Xiao, P. Leung, M. Gershwin, Z. You, Xiong Ma, R. Tang   +20 more
semanticscholar   +1 more source

Impact of Pruritus on Quality of Life and Current Treatment Patterns in Patients with Primary Biliary Cholangitis

Digestive Diseases and Sciences, 2022
Background and Aims Patients with primary biliary cholangitis (PBC) often suffer with pruritus. We describe the impact of pruritus on quality of life and how it is managed in a real-world cohort.
M. Mayo, Elizabeth J. Carey, Helen T. Smith, Andrea R. Mospan, M. McLaughlin, A. Thompson, H. Morris, Robert Sandefur, W. Kim, C. Bowlus, Cynthia Levy   +10 more
semanticscholar   +1 more source