Background Evidence on the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis is limited and conflicting. The primary objective of the Hip Injection Trial (HIT) is to compare pain intensity over 6 months, in people with hip ...
Zoe Paskins +19 more
doaj +1 more source
Laying the foundation for an International Classification of Functioning, Disability and Health Core Set for community-dwelling elderly adults in primary care: the clinical perspective identified in a cross-sectional study [PDF]
Stephanie Book +6 more
openalex +1 more source
What palliative patients and their carers need at home and what a primary health care team can offer – first pilot study in Slovenia [PDF]
Vesna Homar, Urša Pogačar
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Models of collaboration between psychologist and family doctor: a systematic review of primary care psychology [PDF]
open2noThe prevalence of psychological suffering is greater than the actual request for clinical consultation in Europe (Alonso et al., 2004). In Italy, no more than 5.5% of the population requested psychological assistance during lifetime (Miglioretti ...
Benelli, Enrico, Bianco, Francesca
core +1 more source
Background: Health educators play a vital role in primary care by educating patients on the significance of maintaining good health and preventive measures, especially in the case of chronic illnesses.
Ansif Pallath Majeed +6 more
doaj +1 more source
Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study
Background Antibiotic-induced disturbances of the human microbiota have been implicated in the development of chronic autoimmune conditions. This study aimed to assess whether antibiotic use is associated with the onset of rheumatoid arthritis (RA ...
Alyshah Abdul Sultan +6 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Incremental Cost Estimates for the Patient-Centered Medical Home [PDF]
Based on data from thirty-five primary care practices, analyzes the costs associated with the medical home model, in which primary care practices also provide care coordination, patient education, and related services.
Aimee Williams +7 more
core
The family practitioner family : the use of metaphor in understanding changes in primary health care organizations [PDF]
Current UK health policy guidance locates primary care at the frontiers of health care modernization. New organizational structures have resulted in general practitioner (GP) practices being brought together in Primary Care Groups (PCGs) and Primary Care
Stark, S, Warne, T
core +1 more source

