Results 141 to 150 of about 6,908,138 (351)

Primary care for diabetes in HIV-infected patients [PDF]

open access: yes, 2007
Diabetes mellitus (DM) is a common disorder affecting individuals of all ages. Similar to general population, DM can also be seen in HIV infected cases.
Wiwanitkit, Viroj
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Empirical Evidence for Professional Practice and Public Policies: An Exploratory Study on Social Exclusion in Users of Primary Care Social Services in Spain [PDF]

open access: gold, 2019
Víctor M. Giménez Bertomeu   +3 more
openalex   +1 more source

Substance use disorder approaches in US primary care clinics with national reputations as workforce innovators

open access: green, 2021
Denalee O’Malley   +7 more
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Variation in operation rates by primary care trust [PDF]

open access: bronze, 2005
Paul Aylin   +3 more
openalex   +1 more source

Engaging primary care physicians is critical in the screening and diagnosis of colorectal cancer at safety-net hospital systems

open access: gold, 2023
Katrina Dimaano   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Multimorbidity: Technical Series on Safer Primary Care [PDF]

open access: yes, 2016
No abstract ...
Fischbacher-Smith, Denis   +4 more
core  

A digital solution to streamline access to smoking cessation interventions in England; findings from a primary care pilot (STOPNOW study)

open access: gold, 2021
Austen El‐Osta   +11 more
openalex   +1 more source

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