Results 91 to 100 of about 78,237 (351)
Role of Primary Cilia in Odontogenesis [PDF]
Journal of Dental Research, 2017 Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis.
M, Hampl +6 more
openaire +2 more sources
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis [PDF]
, 2013 The small GTP-binding protein Rab8 is known to play an essential role in intracellular transport and cilia formation. We have previously demonstrated that Rab8a is required for localising apical markers in various organisms.
A. Harada +10 more
core +2 more sources
Untethered Magnetic Microswimmers for Targeted Particle Transport and Flow Manipulation
Advanced Materials Technologies, EarlyView.This work introduces magnetically actuated microswimmers to dynamically reconfigure fluid flow within a single microfluidic device. Multiple homogeneous microswimmers are independently controlled by an external magnetic field to perform translational and rotational motions, thereby inducing real‐time flow manipulation.
Dineshkumar Loganathan +3 more
wiley +1 more source
Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling [PDF]
European Cells & Materials, 2017 Tissue engineering-based therapies targeting cartilage diseases, such as osteoarthritis, require in vitro expansion of articular chondrocytes. A major obstacle for these therapies is the dedifferentiation and loss of phenotype accompanying chondrocyte ...
CL Thompson +8 more
doaj +1 more source
Proteomic Analysis of Mammalian Primary Cilia [PDF]
Current Biology, 2012 The primary cilium is a microtubule-based organelle that senses extracellular signals as a cellular antenna. Primary cilia are found on many types of cells in our body and play important roles in development and physiology. Defects of primary cilia cause a broad class of human genetic diseases called ciliopathies.
Ishikawa, Hiroaki +3 more
openaire +2 more sources
Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. [PDF]
, 2016 Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mitotic cells,
Chen, Ju +2 more
core +2 more sources
Hard‐Magnetic Soft Millirobots in Underactuated Systems
Advanced Robotics Research, EarlyView.This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang +4 more
wiley +1 more source
Redox Biology, 2019 The primary cilium, which protrudes from the cell surface, is associated with the pathogenesis of various diseases, including acute kidney injury (AKI). Primary cilium length dynamically changes during the progression of diseases.
Min Jung Kong +5 more
doaj +1 more source
Alteration of primary cilia in COPD [PDF]
European Respiratory Journal, 2018 Non-differentiated airway epithelial cells display primary cilia and their number is associated with COPD featureshttp://ow.ly ...
Perotin, Jeanne-Marie +7 more
openaire +4 more sources
Mixing and transport by ciliary carpets: a numerical study [PDF]
, 2013 We use a 3D computational model to study the fluid transport and mixing due to the beating of an infinite array of cilia. In accord with recent experiments, we observe two distinct regions: a fluid transport region above the cilia and a fluid mixing ...
Ding, Yang +3 more
core +3 more sources