Results 91 to 100 of about 4,909,079 (394)
Primary cilia signaling mediates intraocular pressure sensation [PDF]
, 2014 Lowe syndrome is a rare X-linked congenital disease that presents with congenital cataracts and glaucoma, as well as renal and cerebral dysfunction. OCRL, an inositol polyphosphate 5-phosphatase, is mutated in Lowe syndrome.
Cantor, Louis B. +13 more
core +2 more sources
Renal epithelial cells retain primary cilia during human acute renal allograft rejection injury
BMC Research Notes, 2019 Objectives Primary cilia are sensory organelles which co-ordinate several developmental/repair pathways including hedgehog signalling. Studies of human renal allografts suffering acute tubular necrosis have shown that length of primary cilia borne by ...
Elizabeth Verghese +9 more
doaj +1 more source
Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2 [PDF]
, 2012 Unidirectional fluid flow plays an essential role in the breaking of left-right (L-R) symmetry in mouse embryos, but it has remained unclear how the flow is sensed by the embryo.
A. Kawasumi +33 more
core +1 more source
Primary Cilia Bend LKB1 and mTOR to Their Will [PDF]
Developmental Cell, 2010 Primary cilia are cell surface organelles that act as sensory antennae for various input signals. In a recent issue of Nature Cell Biology, Boehlke et al. (2010) demonstrate that bending of cilia regulates cell size through a signaling pathway involving the LKB1 and mTOR kinases.
Nicolas Aznar +2 more
openaire +2 more sources
Metachronal motion of artificial magnetic cilia [PDF]
Soft Matter, 2018,14, 3689-3693, 2018 Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling waves propagating along ciliary carpet.
arxiv +1 more source
Template-Free Preparation of Thermoresponsive Mag-netic Cilia Compatible with Biological Conditions [PDF]
Journal of Physical Chemistry C 124 (47), 26068 - 26075 (2020), 2020 Bio-inspired materials are commonly used in the development of functional devices. The fabrication of artificial cilia mimicking the biological functions has emerged as a promising strategy for fluid manipulation in miniaturized systems. In this study, we propose a different physicochemical insight for the preparation of magnetic cilia based on the ...
arxiv +1 more source
Comparative study of the primary cilia in thyrocytes of adult mammals [PDF]
, 2015 Since their discovery in different human tissues by Zimmermann in 1898, primary cilia have been found in the vast majority of cell types in vertebrates.
Fernández-Santos, José María +9 more
core +1 more source
Scientific Reports, 2023 Primary cilia are key regulators of embryo development and tissue homeostasis. However, their mechanisms and functions, particularly in the context of human cells, are still unclear.
Lucia Binó, Lukáš Čajánek
doaj +1 more source
Microfluidic pumping using artificial magnetic cilia [PDF]
. Microsystems & Nanoengineering (2018) 4:11, 2018 One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic cilia with similar asymmetric beating can be useful for fluid manipulations in lab-on-chip devices. In this paper,
arxiv +1 more source
Primary cilia are specialized calcium signaling organelles [PDF]
, 2014 Summary Primary cilia are solitary nonmotile extensions of the centriole found on nearly all nucleated eukaryotic cells between cell divisions. Only ∼200-300 nm in diameter and a few microns long, they are separated from the cytoplasm by the ciliary neck
Clapham, David E. +4 more
core +1 more source