Results 101 to 110 of about 4,814,966 (373)

Primary cilium remodeling mediates a cell signaling switch in differentiating neurons

Science Advances, 2020
Newborn neurons assemble a new primary cilium, leading to a change in the mode of Shh signaling that now directs axon extension. Cellular differentiation leads to the formation of specialized cell types and complex morphological variations.
G. Toro-Tapia, Raman M. Das
semanticscholar   +1 more source

Robust Hypothesis Tests for Detecting Statistical Evidence of 2D and 3D Interactions in Single-Molecule Measurements [PDF]

, 2013
A variety of experimental techniques have improved the 2D and 3D spatial resolution that can be extracted from \emph{in vivo} single-molecule measurements. This enables researchers to quantitatively infer the magnitude and directionality of forces experienced by biomolecules in their native cellular environments.
arxiv   +1 more source

The Primary Cilium in Cell Signaling and Cancer [PDF]

Cancer Research, 2006
Abstract The primary cilium is a microtubule-based antenna-like structure that emanates from the surface of virtually all cells in the mammalian body. It is anchored to the cell by the basal body, which develops from the mother centriole of the centrosome in a manner that is coordinately regulated with the cell cycle.
Edward J. Michaud, Bradley K. Yoder
openaire   +3 more sources

Socioeconomic position and clinical outcomes in patients with myelodysplastic syndromes: A population‐based cohort study

Hematological Oncology, Volume 40, Issue 5, Page 1056-1066, December 2022., 2022
Abstract Low socioeconomic position (SEP) may be associated with adverse outcomes in patients with myelodysplastic syndromes (MDS) inherent to for example, delayed diagnosis or reduced treatment intensity, but firm evidence is limited. In this study, we examined the association between SEP and clinical outcomes.
Tine Bichel Lauritsen, Lene Sofie Granfeldt Østgård, Kirsten Grønbæk, Susanne Oksbjerg Dalton, Jan Maxwell Nørgaard   +4 more
wiley   +1 more source

NPHP proteins are binding partners of nucleoporins at the base of the primary cilium.

PLoS ONE, 2019
Cilia are microtubule-based organelles that protrude from the surface of eukaryotic cells to generate motility and to sense and respond to environmental cues.
T Lynne Blasius, Daisuke Takao, Kristen J Verhey   +2 more
doaj   +1 more source

Transmission Electron Microscopy Tilt-Series Data from In-Situ Chondrocyte Primary Cilia

Data, 2021
The primary cilium has recently become the focus of intensive investigations into understanding the physical structure and processes of eukaryotic cells.
Michael J. Jennings, Timothy C. A. Molteno, Robert J. Walker, Jennifer J. Bedford, John P. Leader, Tony Poole   +5 more
doaj   +1 more source

Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

bioRxiv, 2020
Centriolar satellites are dynamic, membrane-less granules composed of over 200 proteins. They store, modify, and traffic centrosome and primary cilium proteins, and help to regulate both the biogenesis and some functions of centrosomes and cilium.
Ozge Z. Aydin, Sevket Onur Taflan, Can Gurkaslar, E. N. Firat-Karalar   +3 more
semanticscholar   +1 more source

Discrete cilia modelling with singularity distributions [PDF]

, 2007
We discuss in detail techniques for modelling flows due to finite and infinite arrays of beating cilia. An efficient technique, based on concepts from previous ‘singularity models’ is described, that is accurate in both near and far-fields.
A.-K. Tornberg, A.T. Chwang, B.A.A. Orme, C.J. Brokaw, C.J. Tabin, D. J. Smith, E. A. Gaffney, E. Bartha, E. Bartha, E. Lauga, E.O. Tuck, F.A. Meyer, G.J. Hancock, G.K. Batchelor, G.R. Fulford, G.R. Fulford, G.R. Fulford, H. Hagiwara, H. Matsui, H. Matsui, J. McGrath, J. R. Blake, J.H.E. Cartwright, J.J.L. Higdon, J.M. Burgers, J.P.K. Tillett, J.R. Blake, J.R. Blake, J.R. Blake, J.R. Blake, J.R. Blake, K. Kosaki, L. Fauci, M. Eisenbach, M. Salathe, M.E. Staben, M.J. Lighthill, M.J. Sanderson, N. Liron, N. Liron, N. Liron, N. Liron, N. Liron, N. Phan-Thien, N.A. Brown, P. Talbot, R. Tarran, R.C. Boucher, R.E. Johnson, R.G. Cox, R.J. Clarke, S. Childress, S. Gueron, S. Gueron, S. Gueron, S. Nonaka, S. Nonaka, S. Nonaka, W.E. Williams, X.Z. Tang, Y. Okada   +60 more
core   +1 more source

Advances in Hybrid Icing and Frosting Protection Strategies for Optics, Lens, and Photonics in Cold Environments Using Thin‐Film Acoustic Waves

Advanced Engineering Materials, EarlyView.
This article provides a comprehensive overview of fundamentals and recent advances of transparent thin‐film surface acoustic wave technologies on glass substrates for monitoring and prevention/elimination of fog, ice, and frost. Fogging, icing, or frosting on optical lenses, optics/photonics, windshields, vehicle/airplane windows, and solar panel ...
Hui Ling Ong, Zhangbin Ji, Luke Haworth, Yihao Guo, Jaime del Moral, Stefan Jacob, Ana Borras, Agustin R. Gonzalez‐Elipe, Jikai Zhang, Jian Zhou, Glen McHale, Yong‐Qing Fu   +11 more
wiley   +1 more source

AutoCaSc: Prioritizing candidate genes for neurodevelopmental disorders

Human Mutation, Volume 43, Issue 12, Page 1795-1807, December 2022., 2022
Abstract Routine exome sequencing (ES) in individuals with neurodevelopmental disorders (NDD) remains inconclusive in >50% of the cases. Research analysis of unsolved cases can identify novel candidate genes but is time‐consuming, subjective, and hard to compare between labs.
Johann Kaspar Lieberwirth, Benjamin Büttner, Chiara Klöckner, Konrad Platzer, Bernt Popp, Rami Abou Jamra   +5 more
wiley   +1 more source