Results 131 to 140 of about 18,376 (272)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Primary Cilium Disassembly in Mammalian Cells Occurs Predominantly by Whole-Cilium Shedding [PDF]

, 2018
Mary Mirvis, Kathleen A. Siemers, W. James Nelson, Tim Stearns   +3 more
openalex   +1 more source

Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Despite the well‐known risks of tobacco use, tobacco exposure remains a major contributor to morbidity and mortality worldwide. Although cigarette use has declined, the popularity of novel tobacco products (NTPs), such as electronic cigarettes (ECs) and heated tobacco products (HTPs), has increased.
Timothy S. Leach, Steven Albertson, Phillip W. Clapp, Vikram Surendran, Trang Simon, Eric C. Donny, Stephen J. Walker, Anthony Atala, Sean V. Murphy   +8 more
wiley   +1 more source

The mediating role of shame in the relationship between adolescent hairpulling and co‐occurring anxiety and depressive symptomology

JCPP Advances, EarlyView.
This study found that shame is a significant mediator in positive associations between hairpulling severity and depression and anxiety severity within a community sample of adolescents with clinical levels of hair‐pulling severity. It also found high levels of trance‐pulling and post‐pulling rituals.
Talia F. Mayerson, Clare Mackay, Polly Waite   +2 more
wiley   +1 more source

Bi-allelic Mutations in FAM149B1 Cause Abnormal Primary Cilium and a Range of Ciliopathy Phenotypes in Humans [PDF]

, 2019
Ranad Shaheen, Nan Jiang, Fatema Alzahrani, Nour Ewida, Tarfa Al‐Sheddi, Eman Alobeid, Damir Musaev, Valentina Stanley, Mais Hashem, Niema Ibrahim, Firdous Abdulwahab, Abduljabbar Alshenqiti, Fatma Müjgan Sönmez, Nadia Saqati, Hamad Alzaidan, Mohammad M. Al‐Qattan, Futwan Al‐Mohanna, Joseph G. Gleeson, Fowzan S. Alkuraya   +18 more
openalex   +1 more source

Disrupting the Chain of Displaced Aggression: A Review and Agenda for Future Research

Journal of Organizational Behavior, EarlyView.
ABSTRACT Displaced aggression refers to instances in which a person redirects their harm‐doing behavior from a primary to a secondary, substitute target. Since the publication of the first empirical article in 1948, there has been a noticeable surge in research referencing this theory in both management and psychology journals.
Constantin Lagios, Simon Lloyd D. Restubog, Pauline Schilpzand, Kohyar Kiazad, Karl Aquino   +4 more
wiley   +1 more source

CCDC66 regulates primary cilium length and signaling competence via multi-site interactions with transition zone and axonemal proteins [PDF]

, 2022
Deniz Conkar, Ezgi Odabasi, Jovana Deretic, Umut Batman, Kari‐Anne M. Frikstad, Sebastian Patzke, Elif Nur Firat‐Karalar   +6 more
openalex   +1 more source

DOCK8 deficiency presenting with sclerosing cholangitis, raised immunoglobulin E, and bronchiectasis: A fatal pediatric case report

JPGN Reports, EarlyView.
Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou, Kelechi Ugonna, Stephen Hughes, Sanjay Rajwal, Marumbo Mtegha   +4 more
wiley   +1 more source

Loss of a primary cilium in PDAC [PDF]

Cell Cycle, 2017
Tetsuo, Kobayashi, Hiroshi, Itoh
openaire   +2 more sources

Astrocyte-specific inhibition of primary cilium functions improves cognitive impairment during neuroinflammation by suppressing C3-positive reactive astrocyte differentiation [PDF]

, 2023
Nor Atiqah Muhamad, Kohei Masutani, Shota Furukawa, Shunsuke Yuri, Michinori Toriyama, Chuya Matsumoto, Seiya Itoh, Yuichiro Shinagawa, Ayako Isotani, Manami Toriyama, Hiroshi Itoh   +10 more
openalex   +1 more source