Results 81 to 90 of about 1,658,836 (295)

Impact of inquiry-based laboratory activities on understanding heat concepts and self-efficacy in pre-service teachers [PDF]

open access: yesJournal of Pedagogical Research
This study investigates the influence of inquiry-based laboratory activities on the understanding of heat concepts and the self-efficacy beliefs of pre-service primary teachers. Recognizing that both scientific literacy and teaching efficacy are critical
Nikolaos Kyriazis   +2 more
doaj   +1 more source

Educational Partnership in Primary Education

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractThe purpose of this study is to highlight the need for educational partnerships in primary education in order to develop optimal educational process.The paper presents the results of a study conducted at two schools in Alexandria, who developed partnerships with educational authorities, institutions(medical units, police, church), local ...
openaire   +1 more source

Primary Physical Education Teacher Educators’ Professional Learning [PDF]

open access: yes, 2019
Pre-service teachers, teachers and teacher educators, are professionals continuously seeking knowledge to support and guide them in their work. This chapter explores, how initial teacher educators, and specifically Primary Physical Education Teacher Educators (PPETEs) learn as professionals.
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Evaluation of an Alimentary Education Intervention on School Canteen Waste at a Primary School in Bari, Italy [PDF]

open access: gold, 2020
Nicoletta Favuzzi   +6 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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