Results 61 to 70 of about 19,641,486 (386)

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Characteristics and outcomes of COVID-19 patients hospitalized at a Central Hospital in Harare, 2020-2022

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: In June 2021, Zimbabwe experienced a third COVID-19 wave characterized by a 3.5% case fatality rate compared to 1.5% in the first wave and 2.6% in the second wave. Sixty-eight percent of these deaths were among hospitalized patients.
Linda Nyasha Kanzara   +7 more
doaj   +1 more source

Descriptive Epidemiology and Mortality Risk Factors of COVID-19 Outbreak in Delta State, Nigeria, March – August 2020

open access: yesJournal of Interventional Epidemiology and Public Health, 2021
Introduction: The highly contagious Coronavirus Disease 2019 (COVID-19) was first confirmed in Nigeria on February 27, 2020. In Delta State, the first COVID-19 case was recorded on April 7, 2020, which spread across the state.
Adaora Rosemary Ejikeme   +19 more
doaj   +1 more source

Conformal properties of primary fields in a q-deformed theory [PDF]

open access: yesJournal of Physics A: Mathematical and General, 1992
10 pages, (Plain Tex), NUS/HEP ...
Oh, C.H., Singh, K.
openaire   +4 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Matrix Description of Intersecting M5 Branes

open access: yes, 1998
Novel 3+1 dimensional N=2 superconformal field theories (with tensionless BPS string solitons) are believed to arise when two sets of M5 branes intersect over a 3+1 dimensional hyperplane.
Kachru, Shamit, Oz, Yaron, Yin, Zheng
core   +2 more sources

The Effect of $w-term$ on Visibility Correlation and Power Spectrum Estimation [PDF]

open access: yes, 2009
Visibility-visibility correlation has been proposed as a technique for the estimation of power spectrum, and used extensively for small field of view observations, where the effect of $w-term$ is usually ignored.
Ali   +18 more
core   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Vacuum Expectation Values from a variational approach

open access: yes, 1997
In this letter we propose to use an extension of the variational approach known as Truncated Conformal Space to compute numerically the Vacuum Expectation Values of the operators of a conformal field theory perturbed by a relevant operator. As an example
Acerbi   +44 more
core   +1 more source

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