Results 71 to 80 of about 6,237,714 (303)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Knowledge, risk perception and uptake of COVID-19 vaccination among internally displaced persons in complex humanitarian emergency setting, Northeast Nigeria

open access: yesBMC Public Health
Background Owing to crowded and unsanitary conditions, internally displaced persons (IDPs) have an increased risk of COVID-19 infection. Adoption of COVID-19 preventive measures among this population is premised on accurate information, adequate ...
Saheed Gidado   +21 more
doaj   +1 more source

Epidemiological profile of the Ebola virus disease outbreak in Nigeria, July-September 2014

open access: yesThe Pan African Medical Journal, 2015
INTRODUCTION: in July 2014, Nigeria experienced an outbreak of Ebola virus disease following the introduction of the disease by an ill Liberian Traveler.
Emmanuel Onunche Musa   +17 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Management of chlamydia and gonorrhoea infections diagnosed in primary care using a centralised nurse-led telephone-based service: mixed methods evaluation

open access: yesBMC Family Practice, 2020
Background Up to 18% of genital Chlamydia infections and 9% of Gonorrhoea infections in England are diagnosed in Primary Care. Evidence suggests that a substantial proportion of these cases are not managed appropriately in line with national guidelines ...
Jeremy Horwood   +6 more
doaj   +1 more source

Development of a simple and effective online training for health workers: results from a pilot in Nigeria

open access: yesBMC Public Health, 2022
Background Health workers (HWs) in Africa face challenges accessing and learning from existing online training opportunities. To address these challenges, we developed a modular, self-paced, mobile-ready and work-relevant online course covering ...
Marshall P. Thomas   +11 more
doaj   +1 more source

Trump Still On Top In NH, Big Battle For Second, Most Voters Still Undecided 1/20/16 [PDF]

open access: yes, 2016
Donald Trump has maintained his double digit lead in the New Hampshire Primary race while the rest of the field remains tightly packed. However, Trump continues to be the candidate that New Hampshire Republicans say they are least likely to vote for ...
Survey Center, UNH
core   +1 more source

Magnetic field, chemical composition and line profile variability of the peculiar eclipsing binary star AR Aur

open access: yes, 2010
AR Aur is the only eclipsing binary known to contain a HgMn star, making it an ideal case for a detailed study of the HgMn phenomenon. HgMn stars are a poorly understood class of chemically peculiar stars, which have traditionally been thought not to ...
Adelman   +33 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

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