Results 81 to 90 of about 6,237,714 (303)

Prevalence and Risk Factors of Elevated Blood Lead in Children in Gold Ore Processing Communities, Zamfara, Nigeria, 2012

open access: yesJournal of Health and Pollution, 2016
Background. In March 2010, Medecins Sans Frontieres/Doctors Without Borders detected an outbreak of acute lead poisoning in Zamfara State, northwestern Nigeria, linked to low-technology gold ore processing.
John A. Kaufman   +10 more
doaj   +1 more source

Cryogenic flux-concentrator [PDF]

open access: yes, 1969
Flux concentrator has high primary to secondary coupling efficiency enabling it to produce high magnetic fields.
Bailey, B. M., Brechna, H., Hill, D. A.
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Observation of the east-west anisotropy of the atmospheric neutrino flux [PDF]

open access: yes, 1999
The east-west anisotropy, caused by the deflection of primary cosmic rays in the Earth's magnetic field, is observed for the first time in the flux of atmospheric neutrinos.
A. Habig   +135 more
core   +3 more sources

A large scale coherent magnetic field: interactions with free streaming particles and limits from the CMB

open access: yes, 2011
We study a homogeneous and nearly-isotropic Universe permeated by a homogeneous magnetic field. Together with an isotropic fluid, the homogeneous magnetic field, which is the primary source of anisotropy, leads to a plane-symmetric Bianchi I model of the
Adamek, Julian   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Implementing the routine immunisation data module and dashboard of DHIS2 in Nigeria, 2014–2019

open access: yesBMJ Global Health, 2020
In 2010, Nigeria adopted the use of web-based software District Health Information System, V.2 (DHIS2) as the platform for the National Health Management Information System. The platform supports real-time data reporting and promotes government ownership
Faisal Shuaib   +22 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Single-crystal growth of the ternary BaFe$_2$As$_2$ phase using the vertical Bridgman technique

open access: yes, 2008
Ternary Ba-Fe-As system has been studied to determine a primary solidification field of the BaFe$_2$As$_2$ phase. We found that the BaFe$_2$As$_2$ phase most likely melts congruently and primarily solidifies either in the FeAs excess or Ba$_{x}$As$_{100 ...
Matan, Kittiwit   +3 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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