Results 101 to 110 of about 2,092,566 (334)

Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records

open access: yesBMC Musculoskeletal Disorders, 2017
Background Knee problems are common in children and adolescents. Despite this, little is known about the epidemiology of knee problems in children and adolescents who consult in general practice.
Zoe A. Michaleff   +4 more
doaj   +1 more source

"When I lost it, they dragged me out": How Care Encounters Empower Marginalized Young Adults' Mental Health Care-Seeking [PDF]

open access: yesarXiv
CSCW research has long explored ways to enhance the well-being of marginalized populations. This study examines how young adults with diverse marginalized identities navigate their mental health care-seeking journeys through in-depth interviews and visual elicitation methods. Our research with 18 U.S. participants reveals predominantly \textit{passive}
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Key service delivery processes, challenges and barriers to healthcare access for managing diabetes outside target HbA1c levels in primary care settings in Qatar: a qualitative inquiry of healthcare professionals’ and service users’ perspectives

open access: yesBMJ Public Health
Introduction Globally, diabetes constitutes a major proportion of non-communicable diseases. Qatar has one of the highest prevalences of diabetes worldwide and a high proportion of people visiting non-communicable disease clinics in primary care settings
Mohamed Ahmed Syed   +4 more
doaj   +1 more source

HAPI-FHIR Server Implementation to Enhancing Interoperability among Primary Care Health Information Systems in Sri Lanka: Review of the Technical Use Case [PDF]

open access: yesEuropean Modern Studies Journal 2024
This review underscores the vital role of interoperability in digital health, advocating for a standardized framework. It focuses on implementing a Fast Healthcare Interoperability Resources (FHIR) server, addressing technical, semantic, and process challenges.
arxiv  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

COVID-19 testing, incidence, and positivity trends among school age children during the academic years 2020–2022 in the State of Qatar: special focus on using CDC indicators for community transmission to evaluate school attendance policies and public health response

open access: yesBMC Pediatrics
Background There exists a gap in our understanding of the age-dependent epidemiological dynamics of SARS-CoV-2 among school-age children in comparison to adults within the State of Qatar.
Mohamed Ghaith Al-Kuwari   +8 more
doaj   +1 more source

Primary health care in an academic medical center. [PDF]

open access: bronze, 1978
S B Thacker   +3 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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