Results 11 to 20 of about 18,607 (256)
Frontiers in Immunology, 2023 The transition from pediatric to adult care is a critical milestone in managing children, especially in those with complex chronic conditions. It involves ensuring the patient and family adapt correctly to the new phase, maintaining continuity of ongoing
María Alejandra Mejía González +10 more
doaj +1 more source
Recurrent pyogenic infections caused by a novel Gln1420* mutation in the C3 gene
Frontiers in Pediatrics, 2022 C3 is a crucial protein of the complement system. Congenital C3 deficiency is extremely rare and manifests through recurrent, severe infections and should always be considered as a differential diagnosis of recurrent pyogenic infections. We report a case
Pedro Simão Coelho +8 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2022 Background The “Primary Immunodeficiencies (PIDs) principles of care” were published in 2014 as the gold standard for care of patients with PIDs, setting a common goal for stakeholders to ensure that patients with PID have access to appropriate care and ...
Leire Solís +8 more
doaj +1 more source
Primary immunodeficiency [PDF]
Allergy, Asthma & Clinical Immunology, 2018 Primary immunodeficiency disorder (PID) refers to a large heterogeneous group of disorders that result from defects in immune system development and/or function. PIDs are broadly classified as disorders of adaptive immunity (i.e., T cell, B-cell or combined immunodeficiencies) or of innate immunity (e.g., phagocyte and complement disorders).
McCusker, Christine +2 more
openaire +4 more sources
Sequence-structure based prediction of pathogenicity for amino acid substitutions in proteins associated with primary immunodeficiencies [PDF]
Frontiers in ImmunologyAnton Zadorozhny +2 more
exaly +2 more sources
Frontiers in Immunology, 2022 Autoimmune lymphoproliferative syndrome (ALPS) is a rare primary immune disorder characterized by impaired apoptotic homeostasis. The clinical characteristics include lymphoproliferation, autoimmunity (mainly cytopenia), and an increased risk of lymphoma.
Laura Batlle-Masó +34 more
doaj +1 more source
Primary immunodeficiency and the microbiome
Current Opinion in Pediatrics, 2021 Purpose of review The current understanding of the relationship of the microbiota to clinical manifestation in patients with primary immunodeficiency, specifically the inflammatory processes caused by or that result in microbial dysbiosis, and their potential therapeutic options in primary immunodeficiency diseases (PID), is ...
Maryam Ali, Al-Nesf +2 more
openaire +2 more sources
PRIMARY IMMUNE DEFICIENCIES – PRINCIPLES OF CARE
Frontiers in Immunology, 2014 Primary Immune Deficiencies (PIDs) are a growing group of over 230 different disorders caused by ineffective, absent or an increasing number of gain of function mutations in immune components (mainly cells and proteins).
Helen eChapel +7 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 The velocity of the COVID-19 pandemic spread and the variable severity of the disease course has forced scientists to search for potential predictors of the disease outcome.
Anna Bobcakova +10 more
doaj +1 more source
Management of a Patient with Cardiovascular Disease Should Include Assessment of Primary and Secondary Immunodeficiencies: Part 1—Primary Immunodeficiencies [PDF]
Healthcare (Switzerland)Zbigniew Bartuzi +2 more
exaly +2 more sources