Use of low-dose trimethoprim-sulfamethoxazole thrice weekly for primary and secondary prophylaxis of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients [PDF]
Daniel S. Stein+7 more
openalex +1 more source
This study identifies a novel mechanism of nasopharyngeal carcinoma (NPC) cisplatin chemoresistance that DDAH1 expression is associated with cisplatin resistance in NPC cells primarily through the enhancement of the phosphoinositide Janus kinase 2 (JAK2)‐signal transducer and activator of transcription 3 (STAT3) pathway.
Jin‐Hao Yang+10 more
wiley +1 more source
Indocyanine Green (ICG)‐guided lung cancer surgery efficacy varies significantly among patients. This study identifies tumor macrophage content as a predictive biomarker. Macrophages are primary ICG reservoirs, storing seven‐fold more ICG than cancer cells.
Yue Yan+13 more
wiley +1 more source
Bone marrow transplantation (BMT) in Europe for primary immunodeficiencies other than severe combined immunodeficiency: a report from the European Group for BMT and the European Group for Immunodeficiency [PDF]
Alain Fischer+9 more
openalex +1 more source
Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga+13 more
wiley +1 more source
Association of Epstein-Barr virus types 1 and 2 with acquired immunodeficiency syndrome-related primary central nervous system lymphomas [letter; comment] [PDF]
CJ Gunthel+4 more
openalex +1 more source
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen+17 more
wiley +1 more source
On the classification of primary immunodeficiencies
C. Pieraert, J. P. Farriaux, G Fontaine
openalex +1 more source
Translation of a Human‐Based Malaria‐on‐a‐Chip Phenotypic Disease Model for In Vivo Applications
Inoculation of the Malaria‐on‐a‐Chip model with human erythrocytes infected with Plasmodium falciparum can support the entire intraerythrocytic lifecycle for 7 days in vitro. Utilizing this human‐based, serum‐free model provides an alternative to animal testing by introducing a human‐based, preclinical alternative for antimalarial therapeutic delivery.
Michael J. Rupar+15 more
wiley +1 more source