Results 121 to 130 of about 220,119 (313)

Novel gene therapy advances for treating primary immunodeficiency disorders - an update. [PDF]

Ann Med Surg (Lond), 2023
Amin R, Darwin R, Chakraborty S, Dey BK, Dhama K, Emran TB.   +5 more
europepmc   +1 more source

(4) IMMUNOLOGIC ANALYSIS OF PERIPHERAL BLOOD LYMPHOCYTES FROM PATIENTS WITH PRIMARY IMMUNODEFICIENCY

, 1981
Hiroaki Mitsuya
openalex   +2 more sources

LncRNA TMEM99 Complexes with IGF2BP2 to Inhibit Autophagy in Lung Adenocarcinoma

Advanced Science, EarlyView.
LncRNA TMEM99 is significantly upregulated in lung adenocarcinoma (LUAD) and correlates with poor prognosis. It promotes LUAD cell proliferation, migration, and invasion while suppressing autophagy. Mechanistically, TMEM99 binds FUBP3 and recruits IGF2BP2 in an m⁶A‐dependent manner to stabilize and enhance p21 mRNA translation, uncovering a novel ...
Zhigang Wu, Yue Zhao, Yizhou Peng, Pengcheng Liu, Qixuan Huang, Yang Wo, Yunjian Pan, DongDong Zheng, Chongze Yuan, Yan Shang, Xiao Chen, Hui Hong, Yihua Sun   +12 more
wiley   +1 more source

Guardians of Immunity: Advances in Primary Immunodeficiency Disorders and Management. [PDF]

Cureus, 2023
Peddi NC, Vuppalapati S, Sreenivasulu H, Muppalla SK, Reddy Pulliahgaru A.   +4 more
europepmc   +1 more source

CXCR-4 Is Expressed by Primary Macrophages and Supports CCR5-Independent Infection by Dual-Tropic but Not T-Tropic Isolates of Human Immunodeficiency Virus Type 1 [PDF]

, 1998
Yanjie Yi, Shalini Rana, Julie D. Turner, Nathan Gaddis, Ronald G. Collman   +4 more
openalex   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu, Yinhao Chen, Hongyi Lin, Jinpeng Lu, Yu Pan, Ge Li, Yongding Wu, Haoxiang Zhang, Xiaoxiao Huang, Yiting Chen, Huangjing Chen, Long Jin, Min Huang, Chengyu Liao, Long Huang, Yifeng Tian, Zuwei Wang, Qiaowei Li, Shi Chen   +18 more
wiley   +1 more source

Non-infectious Pulmonary Complications in Children with Primary Immunodeficiency. [PDF]

Clin Med Insights Pediatr, 2023
Mongkonsritragoon W, Srivastava R, Seth D, Navalpakam A, Poowuttikul P.   +4 more
europepmc   +1 more source

Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity

, 1992

openalex   +1 more source

Prediction of Lung Cancer Metastasis Risk Based on Single‐Cell Metabolic Profiling of Circulating Tumor Cells

Advanced Science, EarlyView.
A self‐developed CTC sorting and capture platform enabled single‐cell metabolomics of patient/animal CTCs, revealing brain/bone metastasis‐specific metabolic signatures. A classification model developed from these signatures predicted lung cancer metastasis risk, outperforming traditional markers and total CTC counts (AUCs:89 brain = 0.74; bone = 0.92).
Yang Xu, Xuesen Hu, Yuan Yuan, Wenwen Liu, Jian Wang, Chunhui Yang, Xianzhe Shi, Wangshu Qin, Liliang Wen, Manqing Lin, Yinuo Jin, Wei Wang, Chunxiu Hu, Guowang Xu, Qi Wang   +14 more
wiley   +1 more source

Subcutaneous immunoglobulin therapy for adult patients with primary immunodeficiency disease: Qatar experience. [PDF]

Qatar Med J, 2023
Thalappil S, Khalil S, Hassini S, Al-Nesf M.   +3 more
europepmc   +1 more source