Results 131 to 140 of about 322,522 (245)

From idiopathic infectious diseases to novel primary immunodeficiencies [PDF]

, 2005
Jean‐Laurent Casanova, Claire Fieschi, Jacinta Bustamante, Janine Reichenbach, Natasha Remus, Horst von Bernuth, Capucine Pïcard   +6 more
openalex   +1 more source

A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo

American Journal of Hematology, EarlyView.
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong, Tamara Wais, Cecilia Varga, Christina Schueller, Sarada Achyutuni, Robert Kralovics   +5 more
wiley   +1 more source

Current status of BCG and OPV vaccination in children with primary immunodeficiency in Chongqing, China. [PDF]

Medicine (Baltimore)
Liu Y, Zhang Y, Ning Y, Zhang Z, Wang Q, Xie W, Yang H, Chen L, Zhao H, Xu J.   +9 more
europepmc   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Characteristics of Secondary Malignancy Among Children With Primary Immunodeficiency Disorders in Saudi Arabia. [PDF]

Cureus
Alnakhli A, Almanjomi F, Alrasheedi H, Alghamdi HA, Mobarak N.   +4 more
europepmc   +1 more source

JOB'S SYNDROME: RECURRENT PULMONARY INFECTIONS IN PRIMARY IMMUNODEFICIENCY, A CASE REPORT [PDF]

, 2018

openalex   +1 more source

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

Seamlessly Overcoming Biological Barriers with a Small Photosensitizer to Treat Metastatic Tumors with Photodynamic Therapy

Angewandte Chemie, EarlyView.
LUZ 51 is a relatively small and amphiphilic photosensitizer that accumulates in poorly‐vascularized tumors, is rapidly internalized by cancer cells, does not elicit skin photosensitivity and triggers robust immunological responses that reduce spontaneous metastasis.
Mafalda Penetra, Bárbara Lima, João P. A. Campos, Sara M. A. Pinto, Fábio A. Schaberle, Mariette M. Pereira, Luis G. Arnaut, Lígia C. Gomes‐da‐Silva   +7 more
wiley   +2 more sources

Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency. [PDF]

Mol Ther Nucleic Acids
Fiduccia I, Vitale E, Varrica R, Ricci D, Marino S, Zito A, Pace A, Colige A, Moutschen M, Borutzki Y, Bileck A, Meier-Menches SM, Lentini L, Pibiri I.   +13 more
europepmc   +1 more source

Does Advoy.com™ help patients with primary immunodeficiency diseases experience that their life situation has improved?

, 2010
Janne Björkander, Carina Berterö
openalex   +2 more sources