Results 131 to 140 of about 194,686 (217)

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li   +5 more
wiley   +1 more source

Accuracy and reproducibility of ChatGPT responses to real‐world drug information questions

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract Introduction The expanding use of Chat Generative Pre‐Trained Transformer (ChatGPT, OpenAI, San Francisco, CA) for drug information may enhance access to information. However, it is crucial to assess the accuracy and reproducibility of ChatGPT responses to drug information questions, examining its utility and limitations in clinical decision ...
Shikha Khatri   +3 more
wiley   +1 more source

A single-center experience of COVID-19 infection in patients with primary immunodeficiency. [PDF]

open access: yesJ Allergy Clin Immunol Glob
Zhou JJ   +11 more
europepmc   +1 more source

A Preliminary Association Study of H19 Non‐Coding Gene Variants With Risk of Non‐Hodgkin Lymphoma: A Case–Control Study and Computational Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Non‐Hodgkin lymphoma (NHL) is a kind of frequently occurring malignant tumor of the lymphoid hematopoietic system in the world. NHL comprises a large group of diverse lymphoid malignancies involving either the lymph nodes or extra nodal sites. It is more prevalent in males living in more developed countries over the age of 60 years.
Sara Kashani   +5 more
wiley   +1 more source

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao   +4 more
wiley   +1 more source

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez   +8 more
wiley   +1 more source

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