Results 211 to 220 of about 220,119 (313)
High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys [PDF]
Ousmane M. Diop+9 more
openalex +1 more source
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao+12 more
wiley +1 more source
Efficacy, Safety, Tolerability, and Serum IgG Trough Levels of Hyaluronidase-Facilitated Subcutaneous Immunoglobulin 10% in US Pediatric Patients with Primary Immunodeficiency Diseases. [PDF]
Patel NC+11 more
europepmc +1 more source
The interaction of tislelizumab with PD‐1/PD‐L1 in the tumor microenvironment. Tislelizumab targets PD‐1 on T cells, blocking its interaction with PD‐L1 on tumor cells. This action is facilitated by a modified F(ab) region that limits Fc‐γ receptor binding, thereby enhancing the antitumor immune response. ABSTRACT Tislelizumab is a next‐generation PD‐1
Thy T. Nguyen+4 more
wiley +1 more source
fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study. [PDF]
Čižnár P+11 more
europepmc +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui+2 more
wiley +1 more source
Lymphoproliferation, Autoimmunity, and Recurrent Infections: Which Primary Immunodeficiency? [PDF]
Öztürk G+8 more
europepmc +1 more source