Results 21 to 30 of about 492,046 (298)

Minor Clinical Impact of COVID-19 Pandemic on Patients With Primary Immunodeficiency in Israel

open access: yesFrontiers in Immunology, 2021
In the last few months the world has witnessed a global pandemic due to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection causing coronavirus disease 2019 (COVID-19).
Nufar Marcus   +55 more
doaj   +1 more source

Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]

open access: yes, 2014
The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis   +1 more
core   +4 more sources

HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency. [PDF]

open access: yes, 2017
Most studies of HIV latency focus on the peripheral population of resting memory T cells, but the brain also contains a distinct reservoir of HIV-infected cells in microglia, perivascular macrophages, and astrocytes.
Alvarez-Carbonell, David   +4 more
core   +1 more source

Impact of Human Immunodeficiency Virus in the Pathogenesis and Outcome of Patients with Glioblastoma Multiforme. [PDF]

open access: yes, 2016
BackgroundImprovement in antiviral therapies have been accompanied by an increased frequency of non-Acquired Immune Deficiency Syndrome (AIDS) defining malignancies, such as glioblastoma multiforme.
Bui, Timothy T   +5 more
core   +1 more source

Primary Immunodeficiencies [PDF]

open access: yes, 2008
Primary immunodeficiencies (PIDs), once considered to be very rare, are now increasingly recognized because of growing knowledge in the immunological field and the availability of more sophisticated diagnostic techniques and therapeutic modalities [161].
Elizabeth Drewe, Richard Powell
openaire   +2 more sources

Update in Primary Immunodeficiencies.

open access: yesActa bio-medica : Atenei Parmensis, 2020
Primary immunodeficiencies (PIDs) are inherited disorders classically characterized by increased susceptibility to infections. Nevertheless, in the last two decades, genomic analysis (such as NGS) coupled with biochemical and cellular studies led to a more accurate definition for a growing number of novel genetic disorders associated with PIDs.
Leonardi, Lucia   +12 more
openaire   +4 more sources

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

open access: yes, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo   +11 more
core   +3 more sources

A Computational Pipeline for the Diagnosis of CVID Patients

open access: yesFrontiers in Immunology, 2019
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses caused by
Annelies Emmaneel   +13 more
doaj   +1 more source

Comparison of [3H]-Thymidine, Carboxyfluorescein Diacetate Succinimidyl Ester and Ki-67 in Lymphocyte Proliferation

open access: yesFrontiers in Pediatrics, 2022
BackgroundPatients with T cell deficiency <10% of normal proliferation are indicated to receive immune reconstruction by hematopoietic stem cell transplantation (HSCT).
Hsin-Ju Lee   +13 more
doaj   +1 more source

Whole exome sequencing identifies compound heterozygous variants of gene in monozygotic twin patients with common variable immunodeficiency

open access: yesSAGE Open Medicine, 2020
Objectives: A pair of female Malay monozygotic twins who presented with recurrent upper respiratory tract infections, hepatosplenomegaly, bronchiectasis and bicytopenia were recruited in this study.
Adiratna Mat Ripen   +6 more
doaj   +1 more source

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