Gene Editing for the Treatment of Primary Immunodeficiency Diseases. [PDF]
Hum Gene Ther, 2021 With conventional treatments for primary immunodeficiency diseases (PIDs), such as allogeneic stem cell transplantation or autologous gene therapy, still facing important challenges, the rapid development of genome editing technologies to more accurately
Rai R, Thrasher AJ, Cavazza A.
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Impact of Primary Immunodeficiency Diseases on the Life Experiences of Patients in Malaysia From the Caregivers’ Perspective: A Qualitative Study [PDF]
Frontiers in Pediatrics, 2022 IntroductionPrimary immunodeficiency diseases (PIDs) are chronic diseases that affect the various aspects of a patient’s life. However, the impact of living with PIDs is poorly described.ObjectiveThis study aimed to explore the living experience ...
Ruwaydah Ahmed Meelad +10 more
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Rubella virus-associated chronic inflammation in primary immunodeficiency diseases. [PDF]
Curr Opin Allergy Clin Immunol, 2020 Purpose of the review The aim of this article is to summarize recent data on rubella virus (RuV) vaccine in chronic inflammation focusing on granulomas in individuals with primary immunodeficiencies (PIDs). Recent findings The live attenuated RuV vaccine
Perelygina L, Icenogle J, Sullivan KE.
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Screening for primary immunodeficiency diseases by next-generation sequencing in early life. [PDF]
Clin Transl Immunology, 2020 We aimed to use next‐generation sequencing (NGS) for the early diagnosis of primary immunodeficiency diseases (PIDs) and define its effects on medical management for an infant cohort in early life.
Sun J +10 more
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Awareness of primary immunodeficiency diseases at a national pediatric reference center in Peru [PDF]
Einstein (São Paulo), 2021 Objective To investigate the level of awareness of primary immunodeficiency diseases among physicians working at Instituto Nacional de Salud del Niño.
Liz Eliana Veramendi-Espinoza +5 more
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Current status and prospects of primary immunodeficiency diseases in Asia. [PDF]
Genes Dis, 2020 Pilania RK +4 more
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Frontiers in Immunology, 2011 We report the updated classification of primary immunodeficiency diseases, compiled by the ad-hoc Expert Committee of the International Union of Immunological Societies (IUIS). As compared to the previous edition, more than 15 novel disease entities have
Waleed eAl-Herz +23 more
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Hematopoietic Stem Cell Transplantation in Primary Immunodeficiency Diseases: Current Status and Future Perspectives. [PDF]
Front Pediatr, 2019 Primary immunodeficiencies (PID) are disorders that for the most part result from mutations in genes involved in immune host defense and immunoregulation.
Castagnoli R +3 more
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Flow cytometry-based diagnosis of primary immunodeficiency diseases
Allergology International, 2018 Primary immunodeficiencies (PIDs) are a heterogeneous group of inherited diseases of the immune system. The definite diagnosis of PID is ascertained by genetic analysis; however, this takes time and is costly.
Hirokazu Kanegane +13 more
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Inflammatory bowel diseases and primary immunodeficiency diseases
Immunological Medicine, 2019 Recent advances in molecular biology have provided important insights into the genetic background of various inflammatory diseases. In particular, genome-wide association studies of inflammatory diseases have revealed genetic loci that play critical ...
Hirokazu Kanegane
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