Results 41 to 50 of about 605,297 (308)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Semiotic analysis on Malangan Batik for elementary school mathematics learning

Jurnal Elemen, 2022
Among the cultural richness in Indonesia, one of which is the Malangan batik cloth. The use of Malangan batik cloth is not only for clothing and decoration needs but also becomes part of the subject matter.
Dyah Worowirastri Ekowati, Arina Restian, Erna Yayuk, Kamariah Kamariah   +3 more
doaj   +1 more source

Mathematics [PDF]

, 2008
This chapter discusses mathematics. It is part of a collection which examines educational practice and professional thinking from pre-school and primary, through secondary, further and higher education; and locates Scottish education within its social ...
Maclellan, Effie
core  

Dynamic mathematics interviews in primary education: The relationship between teacher professional development and mathematics teaching [PDF]

Mathematics Teacher Education and Development, 2023
In this quasi-experimental study involving 23 fourth grade teachers, we investigated the effect of implementing teacher-child dynamic mathematics interviews to improve mathematics teaching behavior in the classroom. After a baseline period of 13 months, the teachers participated in a professional development program to support the use of dynamic ...
Kaskens, Jarise, van Luit, Johannes E.H., Segers, Eliane, Verhoeven, Ludo, Goei, Sui Lin   +4 more
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Primary School Teachers’ Perspectives on Emergency Remote Teaching of Mathematics: Challenges and Opportunities for the Post-COVID-19 Era

Education Sciences, 2023
In this study, we aimed to determine Cypriot primary mathematics teachers’ perspectives and lived experiences during the transition to emergency remote teaching (ERT) in the early stage of the COVID-19 pandemic. An in-depth online survey combining closed-
Maria Meletiou-Mavrotheris, Panagiota Konstantinou, Konstantinos Katzis, Nayia Stylianidou, Angelos Sofianidis   +4 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Mathematical investigations: A primary teacher educator's narrative journey of professional awareness [PDF]

, 2007
As a teacher educator, I used narrative inquiry to investigate my professional practice in working alongside pre-service primary teachers in mathematics education.
Bailey, Judy
core  

Enhancing teacher education in primary mathematics with mobile technologies [PDF]

, 2016
A challenge of teacher education is to produce graduate primary school teachers who are confident and competent teachers of mathematics. Various approaches to primary school teacher education in mathematics have been investigated, but primary teacher ...
Schuck, S
core   +2 more sources

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source