Results 81 to 90 of about 12,666 (271)
, 2021 BACKGROUND: Lupus membranous nephropathy (LMN) is a rare disease, usually associated with nephrotic syndrome. METHODS: We reviewed the literature by searching for the following terms on Pubmed.gov: lupus nephritis, membranous nephropathy (MN), lupus ...
Moroni, Gabriella +2 more
core +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Recent Progress in Deciphering the Etiopathogenesis of Primary Membranous Nephropathy [PDF]
BioMed Research International, 2017 Primary membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. Discovery of several antibodies has contributed to an increased understanding of MN. Antibodies against the M-type phospholipase A2 receptor (PLA2R) are present in 50–100% with primary MN and are associated with a lower frequency of spontaneous remission.
Andreas Kronbichler +4 more
openaire +4 more sources
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2019 Objective To investigate pathological types and the evolutional features of epidemiology of primary glomerular disease in adult patients with renal biopsy in Handan, Hebei, China. Methods From April 2002 to April 2017, a total of 1627 adult patients with
TIAN Kun +4 more
doaj
Journal of Applied Toxicology, EarlyView.ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza +2 more
wiley +1 more source
Frontiers in ImmunologyRituximab is an established therapy for primary membranous nephropathy, but anti−rituximab antibodies (ARA) have been associated with rituximab treatment failure.
Jianying Guo +7 more
doaj +1 more source
A review of progress on complement and primary membranous nephropathy
MedicinePrimary membranous nephropathy (PMN) is a predominant cause of adult nephrotic syndrome, with its incidence witnessing a progressive surge over time. Approximately 35% to 47% of patients progress to renal failure within 10 years, causing a huge social burden. Within China, the proportion of PMN in primary glomerular disease exhibits a gradual ascension.
Shanshen Yu, Jia Sun
openaire +2 more sources
Clinical, genetic and molecular aspects of membranous nephropathy
, 2011 Membranous Nephropathy (MN) is one of the leading causes of end-stage renal disease (ESRD). MN is an autoimmune disease in which autoantibodies target antigens at the level of the glomerular basement membrane.
Stanescu, H.C.
core
Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng +6 more
wiley +1 more source