Results 101 to 110 of about 5,320,666 (302)

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics (The INTERMAP Study) [PDF]

, 2012
Information on dietary supplements, medications, and other xenobiotics in epidemiologic surveys is usually obtained from questionnaires and is subject to recall and reporting biases.
Holmes, Elaine, Elliott, Paul, Nicholson, J.K., Stamler, Jeremiah, Nicholson, Jeremy K., Elliott, P., Loo, Ruey Leng, Robertson, C.E., Holmes, E., Chan, Queenie, Stamler, J., Brown, Ian J., Brown, I.J., Loo, R.L., Chan, Q., Robertson, Claire E.   +15 more
core   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

primary metabolite

Citation: 'primary metabolite' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09806 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Induction of Barley Silicon Transporter HvLsi1 and HvLsi2, increased silicon concentration in the shoot and regulated Starch and ABA Homeostasis under Osmotic stress and Concomitant Potassium Deficiency

Frontiers in Plant Science, 2017
Drought is one of the major stress factors reducing cereal production worldwide. There is ample evidence that the mineral nutrient status of plants plays a critical role in increasing plant tolerance to different biotic and abiotic stresses.
Seyed A. Hosseini, Anne Maillard, Mohammad R. Hajirezaei, Nusrat Ali, Adrian Schwarzenberg, Frank Jamois, Jean-Claude Yvin   +6 more
doaj   +1 more source

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus

Chemistry & Biodiversity
ABSTRACT The genus Iris L. is one of the largest in the Iridaceae Juss. family, comprising more than 320 species. These plants are widespread across the Northern Hemisphere, particularly in temperate and subtropical climate zones. The greatest species diversity occurs in the
Olha Mykhailenko, Liudas Ivanauskas, Victoriya Georgiyants, Zigmantas Gudžinskas   +3 more
openaire   +3 more sources

Additional file 3: Figure S2. of Symbiosis dependent accumulation of primary metabolites in arbuscule-containing cells

, 2016
Polar primary metabolites which were detectable in arbuscule containing cells of mycorrhizal roots (myc+) and in cortex cells of non-mycorrhizal roots (myc-) of Medicago truncatula or in either of the cell types.
Nicole Gaude (3553535), Silvia Bortfeld (3553538), Alexander Erban (230289), Franziska Krajinski (3553532), Joachim Kopka (4071)   +4 more
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Nutraceutical Profile Characterization in Apricot (Prunus armeniaca L.) Fruits

Plants
This study characterizes the metabolomic profiles of three reference apricot cultivars (‘Bergeron’, ‘Currot’, and ‘Goldrich’) using 1H NMR spectroscopy and untargeted UPLC-QToF MS/MS to support plant breeding by correlating metabolomic data with fruit ...
Germán Ortuño-Hernández, Marta Silva, Rosa Toledo, Helena Ramos, Ana Reis-Mendes, David Ruiz, Pedro Martínez-Gómez, Isabel M. P. L. V. O. Ferreira, Juan Alfonso Salazar   +8 more
doaj   +1 more source