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Microbial production of primary metabolites

Naturwissenschaften, 1980
Microbial production of primary metabolites contributes significantly to the quality of life. Through fermentation, microorganisms growing on inexpensive carbon sources can produce valuable products such as amino acids, nucleotides, organic acids, and vitamins which can be added to food to enhance its flavor or increase its nutritive values.
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Pharmacological Studies on Perazine and its Primary Metabolites

Pharmacopsychiatry, 1989
The study served to answer the question whether metabolites possibly contribute to the clinical actions of the neuroleptic drug perazine. The primary metabolites demethylperazine and perazine sulfoxide were investigated with regard to influences on behavior in mice, to an antiemetic action in dogs, and to a modification of the pressor effect of ...
U, Brand   +3 more
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Primary metabolites from overproducing microbial system using sustainable substrates

Biotechnology and Applied Biochemistry, 2020
AbstractPrimary (or secondary) metabolites are produced by animals, plants, or microbial cell systems either intracellularly or extracellularly. Production capabilities of microbial cell systems for many types of primary metabolites have been exploited at a commercial scale. But the high production cost of metabolites is a big challenge for most of the
Rajesh K. Srivastava   +3 more
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Extraction of Primary and Secondary Metabolites

2005
Several new methods besides the usual organic solvent extraction have been developed over the last few years for the extraction of primary and secondary metabolites. These are: alcohol extraction with various biocompatible solvents, recovery of carboxylic acids and antibiotics with reactive extraction, dissociation extraction, aqueous two-phase ...
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Steroid receptor profiling of vinclozolin and its primary metabolites

Toxicology and Applied Pharmacology, 2006
Several pesticides and fungicides commonly used to control agricultural and indoor pests are highly suspected to display endocrine-disrupting effects in animals and humans. Endocrine disruption is mainly caused by the interference of chemicals at the level of steroid receptors: it is now well known that many of these chemicals can display estrogenic ...
José-Manuel, Molina-Molina   +9 more
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Production of Primary and Secondary Metabolites Using Algae

2017
Over the past few decades, there has been an increase in the number of research studies focused on all aspects of the ecology, physiology, biochemistry, cell biology, molecular biology, systematics and uses of algae. This chapter will provide an overview of the potential human health advantages associated with the use of algae as a source of high-value
Rico, Milagros   +5 more
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Vitamin D metabolites and skeletal consequences in primary hyperparathyroidism

Clinical Endocrinology, 2007
SummaryBackground  Primary hyperparathyroidism (PHPT) is associated with reduced bone mineral density (BMD) mainly at sites rich in cortical bone. However, successful parathyroidectomy causes an increase in BMD especially at sites rich in trabecular bone. Plasma 25‐hydroxyvitamin D (25OHD) levels are typically reduced and plasma 1,25‐dihydroxyvitamin D
Moosgaard, Bjarke   +5 more
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Methods, applications and concepts of metabolite profiling: Primary metabolism

2007
In the 1990s the concept of a comprehensive analysis of the metabolic complement in biological systems, termed metabolomics or alternately metabonomics, was established as the last of four cornerstones for phenotypic studies in the post-genomic era.
Steinhauser, D., Kopka, J.
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Role of primary metabolites in plant defense against pathogens

Microbial Pathogenesis, 2019
Plants under natural environment facing various pathogens, tend to produce defense to maintain their fitness and minimize pathogenic damage. Plant-pathogens interaction is gaining more importance by researches as, their means of the fight are primary metabolites. The ultimate result of either means of defense is pathogenesis or resistance.
Madiha, Zaynab   +5 more
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Antipyrine Clearance and Metabolite Formation in Primary Biliary Cirrhosis

Digestive Diseases and Sciences, 2001
The disposition of antipyrine is altered and may be a prognostic factor in the presence of various types of hepatic dysfunction. The object of the present study was to investigate whether antipyrine clearance and metabolite formation are useful to detect altered metabolic function in primary biliary cirrhosis.
F, Jorquera   +5 more
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