Results 51 to 60 of about 728,235 (280)
Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]
, 2017 Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash +5 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Network during light-induced cotyledons opening and greening in Astragalus membranaceus
Journal of Plant Interactions, 2020 Opening and greening are main characteristics of morphogenesis of cotyledons. For revealing interrelationship between metabolism and morphogenesis, metabolic shifts were analyzed in cotyledon of A.
Nan Yang +8 more
doaj +1 more source
Horticulturae, 2023 Climate change could influence the plant response to drought stress in karst environments. However, fewer related studies have been reported. This study examined the impact of artificial water addition on the accumulation of metabolites of Cymbopogon ...
Aiwei Huang +3 more
doaj +1 more source
The balance between fumarate and malate plays an important role in plant development and postharvest quality in tomato fruit [PDF]
, 2018 Organic acids, produced as intermediates of the tricarboxylic cycle, play a crucial role in the plant primary metabolism and are considered as being ones of the most important quality traits in edible fruits.
Fernie, Alisdair R +5 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Molecules, 2023 Metabolic product accumulation exhibited variations among mulberry (Morus alba L.) leaves (MLs) at distinct growth stages, and this assessment was conducted using a combination of analytical techniques including high-performance liquid chromatography ...
Wenjie Li +10 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Applied Sciences, 2021 This study focuses on the detectable metabolome of high-quality raw hazelnuts (Corylus avellana L.) and on its changes after dry-roasting. Informative fingerprinting was obtained by comprehensive two-dimensional gas chromatography with fast-scanning ...
Marta Cialiè Rosso +10 more
doaj +1 more source
¹³C NMR metabolomics: applications at natural abundance. [PDF]
, 2014 (13)C NMR has many advantages for a metabolomics study, including a large spectral dispersion, narrow singlets at natural abundance, and a direct measure of the backbone structures of metabolites.
Clendinen, Chaevien +7 more
core +3 more sources