Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]
, 2020 Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar +10 more
core +1 more source
Applied Sciences, 2021 This study focuses on the detectable metabolome of high-quality raw hazelnuts (Corylus avellana L.) and on its changes after dry-roasting. Informative fingerprinting was obtained by comprehensive two-dimensional gas chromatography with fast-scanning ...
Marta Cialiè Rosso +10 more
doaj +1 more source
The balance between fumarate and malate plays an important role in plant development and postharvest quality in tomato fruit [PDF]
, 2018 Organic acids, produced as intermediates of the tricarboxylic cycle, play a crucial role in the plant primary metabolism and are considered as being ones of the most important quality traits in edible fruits.
Fernie, Alisdair R +5 more
core
Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression. [PDF]
, 2020 The Western diet contains a high ratio of omega-6 (ω6) to omega-3 (ω3) polyunsaturated fatty acids (PUFA). The prototypical aryl hydrocarbon receptor (AHR) ligand, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), induces CYP1 family enzymes, which can ...
Hammock, Bruce D +5 more
core
Multi-Omics Analyses Detail Metabolic Reprogramming in Lipids, Carnitines, and Use of Glycolytic Intermediates between Prostate Small Cell Neuroendocrine Carcinoma and Prostate Adenocarcinoma. [PDF]
, 2019 As the most common cancer in men, prostate cancer is molecularly heterogeneous. Contributing to this heterogeneity are the poorly understood metabolic adaptations of the two main types of prostate cancer, i.e., adenocarcinoma and small cell ...
Alumkal, Joshi J +8 more
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Frontiers in Plant Science, 2022 The hairy root (HR) culture system is an excellent alternative strategy to the whole plant system for producing valuable compounds. However, selection of suitable Agrobacterium strain for the successful induction of HR is an essential step for enhanced ...
Ramaraj Sathasivam +9 more
doaj +1 more source
Acclimation responses of Arabidopsis thaliana to sustained phosphite treatments [PDF]
, 2013 Phosphite () induces a range of physiological and developmental responses in plants by disturbing the homeostasis of the macronutrient phosphate. Because of its close structural resemblance to phosphate, phosphite impairs the sensing, membrane transport,
Berkowitz, O. +7 more
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Frontiers in Plant Science, 2022 Phosphorus (P) is a vital nutrient for plant growth. P availability is generally low in soils, and plant responses to low P availability need to be better understood. In a previous study, we studied the growth and physiological responses of 24 species to
Franklin Magnum de Oliveira Silva +6 more
doaj +1 more source
Ca2+-Stimulated Catecholamine Release from alpha-Toxin Permeabilized PC12 Cells [PDF]
, 1987 Two possible cellular pathways of catecholamines from the chromaffin vesicles of PC 12 cells to the surrounding medium are explored in this study. The direct one circumventing the cytoplasm can be activated in a-toxin-permeabilized cells with micromolar ...
Ahnert-Hilger, G. +2 more
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Agricultural ScienceShallots (Allium cepa L. var. aggregatum) are strategic horticultural commodities rich in primary metabolite compounds that are important for nutritional value and quality of harvest.
Hardian Ningsih +3 more
doaj +1 more source