Results 91 to 100 of about 379,044 (301)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease [PDF]

, 2017
Huntington's disease is an autosomal dominant inherited neurodegenerative disease with motor symptoms that are variably co-expressed with mood and cognitive symptoms, and in which variable neuronal degeneration is also observed in the basal ganglia and ...
Faull, Richard L. M., Hogg, Virginia M., Luthi-Carter, Ruth, Nana, Alissa L., Oorschot, Dorothy E., Synek, Beth J., Thu, Doris C. V., Tippett, Lynette J., Waldvogel, Henry J.   +8 more
core  

Muscle co-activity tuning in Parkinsonian hand movement : disease-specific changes at behavioral and cerebral level [PDF]

, 2015
We investigated different degrees of muscle co-activity in simple hand movement at behavioral and cerebral level in healthy subjects and Parkinson’s disease (PD) patients. We compared 'singular' movements, dominated by the activity of one agonist muscle,
Conway, B. A., de Jong, B. M., Leenders, K. L., Maurits, N. M., Toxopeus, C. M., Valsan, G., van der Stouwe, A. M. M., Yavuz, P.   +7 more
core   +3 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Temporal and spatial patterns of cortical activation during assisted lower limb movement [PDF]

, 2018
Human gait is a complex process in the central nervous system that results from the integrity of various mechanisms, including different cortical and subcortical structures.
Bütler, L., Haefeli, J., Jäncke, L., Koeneke, S., Riener, R., Wieser, M.   +5 more
core  

All Talk and No Action: A Transcranial Magnetic Stimulation Study of Motor Cortex Activation During Action Word Production [PDF]

, 2011
A number of researchers have proposed that the premotor and motor areas are critical for the representation of words that refer to actions, but not objects. Recent evidence against this hypothesis indicates that the left premotor cortex is more sensitive
Caramazza, Alfonso, Finocchiaro, Chiara, Gangitano, Massimo, Oliveri, Massimiliano, Pascual-Leone, Alvaro, Shapiro, Kevin Alfred   +5 more
core   +1 more source

Multisensory integration and motor resonance in the primary motor cortex

Cortex
Humans are endowed with a motor system that resonates to speech sounds, but whether concurrent visual information from lip movements can improve speech perception at a motor level through multisensory integration mechanisms remains unknown. Therefore, the aim of the study was to explore behavioral and neurophysiological correlates of multisensory ...
Serena Giurgola, Emanuele Lo Gerfo, Alessandro Farnè, Alice C. Roy, Nadia Bolognini   +4 more
openaire   +5 more sources

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Effects on the Motor Cortex in Gamma Rhythm in Terms of Central Pattern Generator

IEEE Access, 2019
The locomotion is one of the basic skills essential for animals' survival. It is a key research field where the locomotion is modulated by the motor cortex.
Qiang Lu, Zhenpeng Ma, Wenfeng Li
doaj   +1 more source