BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. [PDF]
Motor training can induce profound physiological plasticity within primary motor cortex, including changes in corticospinal output and motor map topography.
Chan, Sheila +6 more
core
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Emergent modular neural control drives coordinated motor actions. [PDF]
A remarkable feature of motor control is the ability to coordinate movements across distinct body parts into a consistent, skilled action. To reach and grasp an object, 'gross' arm and 'fine' dexterous movements must be coordinated as a single action ...
Ganguly, Karunesh +4 more
core
Muscle co-activity tuning in Parkinsonian hand movement : disease-specific changes at behavioral and cerebral level [PDF]
We investigated different degrees of muscle co-activity in simple hand movement at behavioral and cerebral level in healthy subjects and Parkinson’s disease (PD) patients. We compared 'singular' movements, dominated by the activity of one agonist muscle,
Conway, B. A. +7 more
core +3 more sources
The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma +5 more
wiley +1 more source
Effects on the Motor Cortex in Gamma Rhythm in Terms of Central Pattern Generator
The locomotion is one of the basic skills essential for animals' survival. It is a key research field where the locomotion is modulated by the motor cortex.
Qiang Lu, Zhenpeng Ma, Wenfeng Li
doaj +1 more source
Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease [PDF]
Huntington's disease is an autosomal dominant inherited neurodegenerative disease with motor symptoms that are variably co-expressed with mood and cognitive symptoms, and in which variable neuronal degeneration is also observed in the basal ganglia and ...
Faull, Richard L. M. +8 more
core
Exploiting Multiple Sensory Modalities in Brain-Machine Interfaces [PDF]
Recent improvements in cortically-controlled brain-machine interfaces (BMIs) have raised hopes that such technologies may improve the quality of life of severely motor-disabled patients.
Hatsopoulos, Nicholas G. +2 more
core +2 more sources
Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz +25 more
wiley +1 more source
Opioid suppression of conditioned anticipatory brain responses to breathlessness [PDF]
© 2017 The Authors Opioid painkillers are a promising treatment for chronic breathlessness, but are associated with potentially fatal side effects. In the treatment of breathlessness, their mechanisms of action are unclear.
Campbell, S.F. +10 more
core +4 more sources

