Biomolecules, 2021 Disability in multiple sclerosis accrues predominantly in the progressive forms of the disease. While disease-modifying treatment of relapsing MS has drastically evolved over the last quarter-century, the development of efficient drugs for preventing or ...
Nik Krajnc, Thomas Berger, Gabriel Bsteh
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Radiologically isolated syndrome and multiple sclerosis [PDF]
, 2017 Background Incidental white matter lesions (WML) are increasingly seen on brain magnetic resonance imaging (MRI) in clinical practice. Demyelination consistent with MS is seen in 0.1–0.7% of the population as evident by autopsy and MRI studies.
AlKhawajah, Mona Marwan +3 more
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Axonal damage accumulates in the progressive phase of multiple sclerosis: three year follow up study [PDF]
, 2005 BACKGROUND: Neurofilament phosphoforms (Nf) are principal components of the axoskeleton released during axonal injury. Cerebrospinal fluid (CSF) levels of Nf phosphoforms might be useful surrogate markers for disability in multiple sclerosis (MS), aid in
Polman, C.H. +9 more
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Assessment of sexual life and social life in people with multiple sclerosis
Health Promotion & Physical Activity, 2022 Introduction: Multiple sclerosis is a debilitating condition that affects the central nervous system and is most common in young people. Over time, the relapses associated with the disease can cause damage, and within ten years of onset, half of patients
Denis Arsovski
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Risk of secondary progressive multiple sclerosis: A longitudinal study.
, 2020 BACKGROUND: The risk factors for conversion from relapsing-remitting to secondary progressive multiple sclerosis remain highly contested. OBJECTIVE: The aim of this study was to determine the demographic, clinical and paraclinical features that influence
Jun, Jae-Kwan +63 more
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Quantification of cerebral tissue volumes in multiple sclerosis: global and regional analysis [PDF]
, 2006 Brain atrophy has been reported in multiple sclerosis (MS). We addressed the question of GM and WM tissue loss in a large population of 597 patients with multiple sclerosis (MS) compared with 104 control subjects using a fully automated, operator ...
Prinster, Anna
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Primary progressive multiple sclerosis in a 10-year-old Nigerian boy
Sahel Medical Journal, 2019 Multiple sclerosis (MS) is generally believed to be extremely rare in black African children, and the primary progressive form is the rarest type. We describe a case of primary progressive multiple sclerosis (PPMS) in a 10-year-old Nigerian boy and ...
Jane Owo Anyiam +3 more
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Combining tractography and cortical measures to test system-specific hypotheses in multiple sclerosis. [PDF]
, 2010 The objective was to test three motor system-specific hypotheses in multiple sclerosis patients: (i) corticospinal tract and primary motor cortex imaging measures differ between multiple sclerosis patients and controls; (ii) in patients, these measures ...
Ciccarelli, Olga +6 more
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Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]
, 2013 Multiple sclerosis is an immune-mediated, demyelinating and neurodegenerative disease that currently lacks any neuroprotective treatments. Innovative neuroprotective trial designs are required to hasten the translational process of drug development.
Coffey, P +31 more
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Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis [PDF]
Arquivos de Neuro-Psiquiatria, 2016 Sleep disorders in patients with multiple sclerosis have various causes and interfere with daytime wakefulness. This study assessed the correlation between fatigue, excessive daytime sleepiness and level of disability.
Douglas Martins Braga +3 more
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