Results 51 to 60 of about 1,039,501 (267)

Primary School Children with Special Education Needs

Психологическая наука и образование (2007. Online), 2016
The paper analyses the modern situation of development in elementary school children. As it is shown, children with special educational needs display a delay in social maturation.
Gavrilushkina O.P., , Egorova M.A.,
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Technology ıntegration in pedagogical processes: digital competence and teaching practices of primary school teachers in Turkey

Discover Education
This study provides a critical and contextual analysis of technology integration and digital transformation in education by examining classroom teachers’ perceptions of digital competencies and their application in pedagogical processes.
Zeliha Alptekin, Ahu Taneri
doaj   +1 more source

ANALISIS KURIKULUM PENDIDIKAN LINGKUNGAN HIDUP PADA SEKOLAH DASAR PEKANBARU

Primary: Jurnal Pendidikan Guru Sekolah Dasar, 2013
The purpose of this research is that to create even distribution and understanding about life areaeducation to primary school students that will obtain students’ attitudes in doing actionsappropriating to the concept of life area education and create an ...
Mahmud Alpusari
doaj   +1 more source

Sex education should begin in primary school

BMJ, 1999
EDITOR—We read with interest the news story about the ChildLine report in which children expressed concerns about puberty.1 We were especially concerned about the dearth of information and support provided by the children's parents. During the past century, there has been an acceleration in the rate of physical growthof children and adolescents ...
O, Ejidokun, D, McNulty, J, Linnane, S, Ramaiah   +3 more
openaire   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Current health status of primary school students: a literature review

Фундаментальная и клиническая медицина
Aim. To assess the health status of primary school stu­dents by the literature review and to analyze current direc­tions in the prevention and treatment of their diseases.Ma­terials and Methods.
N. V. Tapeshkina, K. А. Zakharenkova, L. V. Popkova, L. P. Pochueva, O. P. Vlasova, E. M. Sitnikova   +5 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Food, nutrition and sustainability education in Australian primary schools: a cross-sectional analysis of teacher perspectives and practices

Archives of Public Health
Background Healthy eating patterns from sustainable food systems are crucial for population and planetary health. Primary schools are opportune settings for teaching children about food, nutrition and sustainability (FNS) though little is known about the
Jessica V Kempler, Claire Margerison, Janandani Nanayakkara, Alison Booth   +3 more
doaj   +1 more source