Results 131 to 140 of about 62,620 (348)

PRIMARY SCLEROSING CHOLANGITIS IN CHILDREN AND ADOLESCENTS

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND: Primary sclerosing cholangitis is a rare disease, but its prevalence has been underestimated in children and adolescents due to broad variation in clinical presentation as well as diagnostic challenges in this life period.
Eleonora Druve Tavares FAGUNDES   +3 more
doaj   +1 more source

Fifteen years of clinical liver transplantation [PDF]

open access: yes, 1979
Liver transplantation in humans was first attempted more than 15 yr ago. The 1-yr survival has slowly improved until it has now reached about 50%. In our experience, 46 patients have lived for at least 1 yr, with the longest survival being 9 yr. The high
Abouna   +65 more
core   +1 more source

Diabetes Mellitus is a Risk Factor for Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Diabetes mellitus independently increases the risk of hepatic encephalopathy following TIPS placement in patients with cirrhosis. These findings emphasize the need for careful risk assessment in patients with cirrhosis and portal hypertension complications undergoing TIPS.
Michelle Spaan   +16 more
wiley   +1 more source

Pyoderma Gangrenosum Associated with Sclerosing Cholangitis, Type 1 Diabetes Mellitus and Ulcerative Colitis [PDF]

open access: yes, 2001
We describe the case of a 22-year-old black female with type 1 diabetes mellitus diagnosed when she was 12 years old. She first presented (March 1994) with pustules and ulcerations on the upper and lower limbs, trunk and scalp at the age 17.
A Morbey   +28 more
core   +1 more source

Characterisation and Prognostic Implication of Cholestasis After Burn Injury

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In 532 burn ICU patients, we quantified trajectories of cholestasis markers and validated burn‐associated cholestasis definitions. Bilirubin dynamics, particularly hyperbilirubinemia ≥ 2× ULN within 14 days, independently predicted excess in‐hospital and overall mortality beyond burn and critical‐illness severity, identifying a high‐risk subgroup after
Lorenz Semmler   +16 more
wiley   +1 more source

Preventative care in cholestatic liver disease: Pearls for the specialist and subspecialist

open access: yesLiver Research, 2019
Cholestatic liver diseases (CLDs) encompass a variety of disorders of abnormal bile formation and/or flow. CLDs often lead to progressive hepatic insult and injury and following the development of cirrhosis and associated complications.
Adnan Malik   +4 more
doaj   +1 more source

A New Mutation Causing Progressive Familiar Intrahepatic Cholestasis Type 3 in Association with Autoimmune Hepatitis [PDF]

open access: yes, 2017
Background: Some patients exhibit features of both autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC). Similarly, patients with progressive familial intrahepatic cholestasis type 3 (PFIC3) may share histological features with PSC.
Oliveira, Hugo M.   +5 more
core   +3 more sources

Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis

open access: yesAlimentary Pharmacology and Therapeutics, 2019
Single‐centre studies reported alterations of faecal microbiota in patients with primary sclerosing cholangitis (PSC). As regional factors may affect microbial communities, it is unclear if a microbial signature of PSC exists across different ...
M. Rühlemann   +16 more
semanticscholar   +1 more source

Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response

open access: yesThe FEBS Journal, EarlyView.
Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo   +16 more
wiley   +1 more source

Imaging of Benign Biliary Tract Disease

open access: yesIndian Journal of Radiology and Imaging
This review article discusses the most common benign biliary disorders and the various radiological findings on multiple modalities. A broad spectrum of diseases including various congenital disorders, infective and parasitic etiologies, immunological ...
Samarjit Singh Ghuman   +5 more
doaj   +1 more source

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