Results 31 to 40 of about 675,523 (296)

Prime-boost vaccination of hACE2 transgenic mice with rVSV-msp-SF-Gtc induces a high level of Spike(ΔTM) specific IgG.

open access: yes, 2021
Six-week-old female hACE2 transgenic mice were prime vaccinated with rVSVInd-msp-SF-Gtc and boost vaccinated with rVSVInd-msp-SF-Gtc or rVSVNJ-msp-SF-Gtc two weeks after the prime-vaccination.
Taewoo Kim (1456888)   +30 more
core   +1 more source

Heterologous prime–boost vaccination [PDF]

open access: yesCurrent Opinion in Immunology, 2009
An effective vaccine usually requires more than one time immunization in the form of prime-boost. Traditionally the same vaccines are given multiple times as homologous boosts. New findings suggested that prime-boost can be done with different types of vaccines containing the same antigens.
openaire   +2 more sources

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

open access: yesVaccines, 2021
Heterologous prime-boost strategies are known to substantially increase immune responses in viral vectored vaccines. Here we report on safety and immunogenicity of the poxvirus Modified Vaccinia Ankara (MVA) vectored vaccine expressing four Mycobacterium
Pedro M. Folegatti   +16 more
doaj   +1 more source

Chimpanzee adenoviral vector prime-boost regimen elicits potent immune responses against Ebola virus in mice and rhesus macaques

open access: yesEmerging Microbes and Infections, 2019
In the last few decades, Ebola virus (EBOV) has emerged periodically and infected people in Africa, resulting in an extremely high mortality rate. With no available prophylaxis or cure so far, a highly effective Ebola vaccine is urgently needed.
Xi Yang   +8 more
doaj   +1 more source

Virus-Like Particles Are Efficient Tools for Boosting mRNA-Induced Antibodies

open access: yesFrontiers in Immunology, 2022
mRNA based vaccines against COVID-19 have proven most successful at keeping SARS-CoV-2 pandemic at bay in many countries. Recently, there is an increased interest in heterologous prime-boost vaccination strategies for COVID-19 to maintain antibody ...
Anne-Cathrine S. Vogt   +17 more
doaj   +1 more source

Prime-boost influenza vaccination protects L. sigmodontis-infected mice from challenge infection-induced weight loss.

open access: yes, 2022
(A) Experimental design: C57BL/6 mice were left naïve (black and grey squares) or naturally infected with L. sigmodontis (light and dark blue circles). Mice either received a control injection (open symbols) or were i.p.
Marie-Luise Brunn (6030185)   +4 more
core   +1 more source

A novel candidate HIV vaccine vector based on the replication deficient Capripoxvirus, Lumpy skin disease virus (LSDV)

open access: yesVirology Journal, 2011
Background The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. Methods The safety of LSDV was tested
Johnston Nicolette   +6 more
doaj   +1 more source

Heterologous prime-boost immunization with CoronaVac and Convidecia [PDF]

open access: yes, 2021
ABSTRACT Background The safety and immunogenicity of heterologous prime-boost COVID-19 vaccine regimens with one shot of a recombinant adenovirus type-5-vectored COVID-19 vaccine Convidecia has not been reported.
Jingxin Li   +20 more
openaire   +1 more source

Recombinant BCG-Prime and DNA-Boost Immunization Confers Mice with Enhanced Protection against Mycobacterium kansasii

open access: yesVaccines, 2021
The incidence of infections with nontuberculous mycobacteria (NTM) has been increasing worldwide. The emergence of multidrug-resistant NTM is a serious clinical concern, and a vaccine for NTM has not yet been developed.
Shihoko Komine-Aizawa   +5 more
doaj   +1 more source

Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8+ T Cell Responses

open access: yesMolecular Therapy: Oncolytics, 2020
Cancer vaccination aims at inducing an adaptive immune response against tumor-derived antigens. In this study, we utilize recombinant human adenovirus serotype 5 (rAd5) and recombinant lymphocytic choriomeningitis virus (rLCMV)-based vectors expressing ...
Sandra S. Ring   +7 more
doaj   +1 more source

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