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Six-week-old female hACE2 transgenic mice were prime vaccinated with rVSVInd-msp-SF-Gtc and boost vaccinated with rVSVInd-msp-SF-Gtc or rVSVNJ-msp-SF-Gtc two weeks after the prime-vaccination.
Taewoo Kim (1456888) +30 more
core +1 more source
Heterologous prime–boost vaccination [PDF]
An effective vaccine usually requires more than one time immunization in the form of prime-boost. Traditionally the same vaccines are given multiple times as homologous boosts. New findings suggested that prime-boost can be done with different types of vaccines containing the same antigens.
openaire +2 more sources
Heterologous prime-boost strategies are known to substantially increase immune responses in viral vectored vaccines. Here we report on safety and immunogenicity of the poxvirus Modified Vaccinia Ankara (MVA) vectored vaccine expressing four Mycobacterium
Pedro M. Folegatti +16 more
doaj +1 more source
In the last few decades, Ebola virus (EBOV) has emerged periodically and infected people in Africa, resulting in an extremely high mortality rate. With no available prophylaxis or cure so far, a highly effective Ebola vaccine is urgently needed.
Xi Yang +8 more
doaj +1 more source
Virus-Like Particles Are Efficient Tools for Boosting mRNA-Induced Antibodies
mRNA based vaccines against COVID-19 have proven most successful at keeping SARS-CoV-2 pandemic at bay in many countries. Recently, there is an increased interest in heterologous prime-boost vaccination strategies for COVID-19 to maintain antibody ...
Anne-Cathrine S. Vogt +17 more
doaj +1 more source
(A) Experimental design: C57BL/6 mice were left naïve (black and grey squares) or naturally infected with L. sigmodontis (light and dark blue circles). Mice either received a control injection (open symbols) or were i.p.
Marie-Luise Brunn (6030185) +4 more
core +1 more source
Background The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. Methods The safety of LSDV was tested
Johnston Nicolette +6 more
doaj +1 more source
Heterologous prime-boost immunization with CoronaVac and Convidecia [PDF]
ABSTRACT Background The safety and immunogenicity of heterologous prime-boost COVID-19 vaccine regimens with one shot of a recombinant adenovirus type-5-vectored COVID-19 vaccine Convidecia has not been reported.
Jingxin Li +20 more
openaire +1 more source
The incidence of infections with nontuberculous mycobacteria (NTM) has been increasing worldwide. The emergence of multidrug-resistant NTM is a serious clinical concern, and a vaccine for NTM has not yet been developed.
Shihoko Komine-Aizawa +5 more
doaj +1 more source
Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8+ T Cell Responses
Cancer vaccination aims at inducing an adaptive immune response against tumor-derived antigens. In this study, we utilize recombinant human adenovirus serotype 5 (rAd5) and recombinant lymphocytic choriomeningitis virus (rLCMV)-based vectors expressing ...
Sandra S. Ring +7 more
doaj +1 more source

