Results 101 to 110 of about 1,299,040 (282)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The graph of the square mapping on the prime fields
Discrete Mathematics, 1996 Let \(f: G\to G\) be a map of a finite set into itself. Then \(\text{graph}(G)\) is defined to be the directed graph whose vertices are the elements of \(G\) with a directed edge from \(x\) to \(f(x)\) for all \(x\in G\). In this paper, the action of the map \(f(x)= x^2\) on the multiplicative groups \(F^*_p\) of the prime fields is examined. Let \(C_m\
openaire +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Malaphoric $$Z^\prime $$ Z ′ models for $$b \rightarrow s \ell ^+ \ell ^-$$ b → s ℓ + ℓ - anomalies
European Physical Journal C: Particles and FieldsWe study some phenomenological effects of kinetic mixing between the hypercharge field and a new U(1) gauge field in specific $$Z^\prime $$ Z ′ models that ameliorate the tensions between measurements and Standard Model predictions in $$b \rightarrow s ...
Ben Allanach, Nico Gubernari
doaj +1 more source
Constacyclic codes over finite local Frobenius non-chain rings of length 5 and nilpotency index 4
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020 The family of finite local Frobenius non-chain rings of length 5 and nilpotency index 4 is determined, as a by-product all finite local Frobenius non-chain rings with p5 elements (p a prime) and nilpotency index 4 are given.
Castillo-Guillén C. A. +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Garaev’s inequality in finite fields not of prime order
Online Journal of Analytic Combinatorics, 2008 .
Katz, Nets Hawk, Shen, Chun-Yen
openaire +3 more sources
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source