Results 101 to 110 of about 5,325,381 (300)
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Film Centre group with Prime Minister [PDF]
Film Centre funding announcement. Greg Lee, MP Andrew Saxton, Prime Minister Stephen Harper, MLA Jane Thornethwaite.
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Malaphoric $$Z^\prime $$ Z ′ models for $$b \rightarrow s \ell ^+ \ell ^-$$ b → s ℓ + ℓ - anomalies
We study some phenomenological effects of kinetic mixing between the hypercharge field and a new U(1) gauge field in specific $$Z^\prime $$ Z ′ models that ameliorate the tensions between measurements and Standard Model predictions in $$b \rightarrow s ...
Ben Allanach, Nico Gubernari
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Formal Verification, Integration and Physical Evaluation of Prime-Field Masking on Silicon
The resistance of provably secure masked circuits to physical attacks depends in part on the underlying algebraic group and recombination function. Masking over finite fields of odd prime order has been demonstrated, both in theory and in practice, to ...
Gaëtan Cassiers +4 more
doaj +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Primer for Meitei Mayek for teaching in Kindergarten and Class 1, Board of Secondary Education, Manipur. By L.
Kumar, L. Basanta
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