Results 91 to 100 of about 5,325,381 (300)

Garaev’s inequality in finite fields not of prime order

open access: yesOnline Journal of Analytic Combinatorics, 2008
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Katz, Nets Hawk, Shen, Chun-Yen
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Infinite Towers of Galois Defect Extensions of Kaplansky Fields

open access: yesAnnales Mathematicae Silesianae, 2018
We give conditions for Kaplansky fields to admit infinite towers of Galois defect extensions of prime degree. As proofs of the presented facts are constructive, this provides examples of constructions of infinite towers of Galois defect extensions of ...
Blaszczok Anna
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Programme of Prime Minister Alexander Stubb's Government [PDF]

open access: yes, 2014
The goal of Prime Minister Stubb’s Government is an open, fair and confident Finland. The Government Programme is based on Prime Minister Katainen’s Government Programme as well as the Structural Policy Programme and policies relating to its ...

core  

Sequences in finite fields yielding divisors of Mersenne, Fermat and Lehmer numbers, II [PDF]

open access: yesNotes on Number Theory and Discrete Mathematics
Let ρ be an odd prime ≥ 11. In Part I, starting from an M-cycle in a finite field 𝔽_ρ, we have established how the divisors of Mersenne, Fermat and Lehmer numbers arise.
A. M. S. Ramasamy
doaj   +1 more source

Primes in quadratic fields

open access: yes, 2010
This paper presents algorithms for calculating the quadratic character and the norms of prime ideals in the ring of integers of any quadratic field. The norms of prime ideals are obtained by means of a sieve algorithm using the quadratic character for the field considered.
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The graph of the square mapping on the prime fields

open access: yesDiscrete Mathematics, 1996
Let \(f: G\to G\) be a map of a finite set into itself. Then \(\text{graph}(G)\) is defined to be the directed graph whose vertices are the elements of \(G\) with a directed edge from \(x\) to \(f(x)\) for all \(x\in G\). In this paper, the action of the map \(f(x)= x^2\) on the multiplicative groups \(F^*_p\) of the prime fields is examined. Let \(C_m\
openaire   +1 more source

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