Results 81 to 90 of about 11,676,412 (344)

Multiscale Sieve for Smart Prime Generation and Application in Info-Security, IoT and Blockchain

open access: yesApplied Sciences
The huge computational cost required to test whether a number is prime and the inefficiency of the known sieving algorithms for extremely large inputs have posed significant challenges in computational number theory.
Gerardo Iovane   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

On k-prime graphs

open access: yesOpen Mathematics
In the context of a simple undirected graph GG, a kk-prime labeling refers to assigning distinct integers from the set {k,k+1,…,∣V(G)∣+k−1}\left\{k,k+1,\ldots ,| V\left(G)| +k-1\right\} to its vertices, such that adjacent vertices in GG are labeled with ...
Abughneim Omar A., Abughazaleh Baha’
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Subsets of prime numbers received by means of generalized arithmetic progression

open access: yesДифференциальная геометрия многообразий фигур, 2018
A short historical information about formulas and polynomials gener­ating subsets of prime numbers is given. Examples of subsets of prime numbers by using generalized arithmetic progression are obtained.
V. Malakhovsky
doaj  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The number of rational points of some classes of algebraic varieties over finite fields

open access: yesOpen Mathematics
Let Fq{{\mathbb{F}}}_{q} be the finite field of characteristic pp and Fq*=Fq\{0}{{\mathbb{F}}}_{q}^{* }\left={{\mathbb{F}}}_{q}\backslash \left\{0\right\}.
Zhu Guangyan   +3 more
doaj   +1 more source

Prime number logarithmic geometry on the plane

open access: yes, 2002
We found a regularity of the behavior of primes that allows to represent both prime and natural numbers as infinite matrices with a common formation rule of their rows.
Alexandrov, Lubomir
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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