Results 141 to 150 of about 156,880 (305)
PROBLEMS OF PRIME NUMBERS AND THE PRIME NUMBER CRITERION THEOREM
, 2013 The world scientific community considers a solution of the prime numbers problem and the Riemann Zeta Function Zeros closely connected with prime numbers to be the most significant problems of modern science.
Ushtenov, Esenbek, Mamaraimov, Mukhidin
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Interesting prime numbers and their properties
, 2020 The aim of this bachelor thesis is to introduce special kinds of prime numbers to the reader. The thesis is divided into four parts. The first, introductory, one deals with the definition of prime numbers, provides some basic information about them, and ...
KRATOCHVÍL, Daniel
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About Interval Estimations of the Prime Numbers Maintenance
Безопасность информационных технологий, 2011 In the article, within the framework of confidential information protection tasks, the model of prime and compound numbers formation in an interval ...
V. A. Minaev
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The first prime number with the special property that its addition with reversal gives as result a prime number too is two hundred twenty nine. The prime numbers with this property will be called Luhn prime numbers. In this article we intend to present a
Cira, Octavian, Smarandache, Florentin
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Prime Numbers and Primality Testing
, 2018 The Fundamental Theorem of Arithmetic states that every composite integer can be written as a unique product of prime numbers. As new prime numbers are being discovered, mathematicians continue their search for larger and larger prime numbers.
Chu, Huy
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