Results 151 to 160 of about 143,448 (228)

mRNA prime-boost vaccination promotes clonal continuity in germinal center reactions and broadens SARS-CoV-2 variant coverage. [PDF]

Mol Ther
Ciancaglini M, Fixemer J, Seven C, Dimitrova M, Finozzi D, Weklak D, Kastner AL, Jönsson F, Wagner I, Vincenti I, Peters A, Newby ML, Crispin M, Merkler D, Kreppel F, Pinschewer DD.   +15 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Procedures of data merging in precision cancer medicine: the PRIME-ROSE project. [PDF]

Acta Oncol
Van der Pol H, Kringelbach T, Martin Agudo M, Bratseth Stav G, Fagereng GL, Fiocco M, Sørum Falk R, Homer V, Haj Mohammad S, Timmer H, Verlingue L, Helland Å, Rohrberg K, Lassen U, Halford S, Jalkanen K, Juslin T, Krebs MG, Oliveira J, Baltruskeviciene E, Ojamaa K, Taskén K, Gelderblom H.   +22 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

PRIME: an interpretable artificial intelligence model based on liquid biopsy improves prediction of progression risk in non-small cell lung cancer. [PDF]

Mil Med Res
Wang Y, Xiang YB, Chen XW, Zhang T, Wang JY, Liu WY, Deng L, Wang LH, Gao SG, Bi N.   +9 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Inactivated Avian Infectious Bronchitis Virus Strains M41 and 4-91 Provide Broad Protection Against Multiple Avian Infectious Bronchitis Strains. [PDF]

Vaccines (Basel)
van de Weem NMP, Walczak M, van Rooij L, Hormes FAJ, Hesseling P, Timmers L, Wouters PAWM, Raue R.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Prime mass amino acids: A new numbers based classification of significance to mass spectrometry and protein biology. [PDF]

Eur J Mass Spectrom (Chichester)
Downard KM.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source