Results 81 to 90 of about 147,553 (263)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

On an inequality about Euler's totient function [PDF]

open access: yesNotes on Number Theory and Discrete Mathematics
In this paper, we show that when Nₖ is a primorial and φ(Nₖ) is Euler's totient function, the inequality φ(Nₖ)44.
Cheng-Ting Wang
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Computational challenges and solutions: Prime number generation for enhanced data security.

open access: yesPLoS ONE
This paper addresses the computational methods and challenges associated with prime number generation, a critical component in encryption algorithms for ensuring data security.
Amal Ezz-Eldien   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

On the emergence of the Quanta Prime sequence

open access: yesArab Journal of Basic and Applied Sciences
This paper presents the Quanta Prime Sequence (QPS) and its foundational theorem, showcasing a unique class of polynomials with substantial implications.
Moustafa Ibrahim
doaj   +1 more source

Mersenne Primes in Certain Lucas Sequences [PDF]

open access: yesEPJ Web of Conferences
Prime numbers are the most important numbers in number theory and cryptography. One of such special primes are given by the set of Mersenne primes, that are derived from the form Mn = 2n − 1, where n is a prime number.
Hadi Ahmed H., Hashim Hayder R.
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

A note on Sturm-Liouville problems whose spectrum is the set of prime numbers

open access: yesElectronic Journal of Differential Equations, 2011
We show that there is no classical regular Sturm-Liouville problem on a finite interval whose spectrum consists of infinitely many distinct primes numbers. In particular, this answers in the negative a question raised by Zettl in his book [9].
Angelo B. Mingarelli
doaj  

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