Results 201 to 210 of about 137,442 (242)
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Reprogramming Primordial Germ Cells (PGC) to Embryonic Germ (EG) Cells

Current Protocols in Stem Cell Biology, 2008
AbstractIn this unit we describe the derivation of pluripotent embryonic germ (EG) cells from mouse primordial germ cells (PGCs) isolated from both 8.5‐ and 11.5‐days post‐coitum (dpc) embryos. Once EG cells are derived we explain how to propagate and characterize the cell lines.
Azim Surani
exaly   +3 more sources

Functional primordial germ cell–like cells from pluripotent stem cells in rats

Science, 2022
The in vitro generation of germ cells from pluripotent stem cells (PSCs) can have a substantial effect on future reproductive medicine and animal breeding. A decade ago, in vitro gametogenesis was established in the mouse.
Mami Oikawa   +13 more
semanticscholar   +1 more source

Primordial Germ Cells and Fecundity

Nature, 1966
THE origin of the definitive germ cells of vertebrates from the primordial germ cells of the embryonic period is now widely accepted and has been supported in the case of a few species1–4 by quantitative observations, which make it unnecessary to postulate the neo-formation of germ cells from the somatic elements of the so-called ‘germinal epithelium’.
M W, Hardisty, J, Cosh
openaire   +2 more sources

The Biology of Primordial Germ Cells

European Urology, 1993
Primordial germ cells are the founder cells of the gametes. They arise at the earliest stages of development, and migrate to the genital ridges, where they join the somatic cells of the future gonad. The factors that determine their formation and migration are largely unknown.
openaire   +2 more sources

The induction of the primordial germ cells in the urodeles

Wilhelm Roux' Archiv f�r Entwicklungsmechanik der Organismen, 1974
Xenoplastic recombinates of animal ectodermal caps with the ventral vegetative yolk mass of blastulae of stage 81/2-83/4 ofA. mexicanum, T. alpestris, T. cristatus carnifex andP. waltlii have demonstrated unambiguously that in the urodeles the primordial germ cells-together with other ventro-caudal mesodermal structures-develop from the animal ...
Lien A, Sutasurja, P D, Nieuwkoop
openaire   +2 more sources

From primordial germ cell to primordial follicle: mammalian female germ cell development

genesis, 2006
In mammals, the final number of oocytes available for reproduction of the next generation is defined at birth. Establishment of this oocyte pool is essential for fertility. Mammalian primordial germ cells form and migrate to the gonad during embryonic development. After arriving at the gonad, the germ cells are called oogonia and develop in clusters of
openaire   +2 more sources

Isolation of mouse primordial germ cells

Experimental Cell Research, 1982
Abstract Primordial germ cells (PGCs) were obtained from fetal mouse gonads of both sexes 12 1 2 and 13 1 2 days post coitum (dpc), either by collagenase treatment, or by mechanical procedures with or without prior EDTA treatment.
DE FELICI, MASSIMO, McLaren, A.
openaire   +3 more sources

The mechanical journey of primordial germ cells

American Journal of Physiology-Cell Physiology
Primordial germ cells (PGCs) are the earliest progenitors of germline cells of the gonads in animals. The tissues that arise from primordial germ cells give rise to male and female gametes and are thus responsible for transmitting genetic information to subsequent generations.
Malhar S. Chitnis   +3 more
openaire   +2 more sources

Development of primordial germ cells in the mouse*

Andrologia, 2009
Primordial germ cells in the mouse are known to be derived from the epiblast. They can be identified histochemically, by their high alkaline phosphatase activity. At 8 d post coitum they have been observed within the embryonic part of the egg cylinder, at the posterior end of the primitive streak.
openaire   +2 more sources

Primordial Germ Cells and Germ Line Stem Cells

2015
Germ cells are a sexual reproductive cell type at any stage from primordial germ cells (PGCs) to mature gametes. Germ line stem cells are important for genetic transmission to future generations. In this review, we focus on female germ line stem cells (FGSCs), spermatogonial stem cells (SSCs), and PGCs.
Ji Wu   +5 more
openaire   +1 more source

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